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Quote of the day

'By far the greatest danger of Artificial Intelligence is that people conclude too early that they understand it'

 

Eliezer Yudkowsky

Against the biological clock:

RATE THIS! +41
Posted in Science on 3rd Aug, 2014 11:46 PM by AlexMuller
Aubrey de Grey is cofounder and Chief Science Officer of the SENS Research Foundation and faculty at Singularity University’s November Exponential Medicine conference, an event exploring the healthcare impact of technologies like low-cost genomic sequencing, artificial intelligence, synthetic biology, gene therapy, and more.
 
To Dr. de Grey, the body is a machine. Just as a restored classic car can celebrate its hundredth birthday in peak condition, in the future, we’ll maintain our bodies’ cellular components to stave off the diseases of old age and live longer, healthier lives. Recently speaking to participants in Singularity University’s graduate studies program, de Grey said the greatest challenge in aging research today is less of a technical nature, more a misguided focus in the mainstream.
 
Most approaches to age-related disease aim to manage symptoms. They have contributed to longer life expectancy and eased complications, but because treatments interfere with the body’s finely tuned systems, they can have nasty side effects and are ultimately powerless (even with advances) to reverse age-related illness. Why? “Aging is a side effect of being alive in the first place,” says de Grey.
 
Metabolic processes drive the day-to-day business of living, but they also inevitably cause cellular damage. The body’s range of self-repair mechanisms don’t take care of everything. Eventually, a lifetime of accumulated damage causes the familiar signs of aging like “thinning skin, cloudy eyes, muscles sapped of strength, heart disease, and cognitive decline.”
 
De Grey is known for his research into engineered negligible senescence. Negligible senescence is a term used to describe certain animals that don’t display symptoms of aging. De Grey believes we can use biotechnology to engineer negligible senescence in humans, and he cofounded the SENS Research Foundation to lead the way.

Tags: agingbiologyhealthmedicinedisease

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Comments

Author: Guest
Posted: 2014-08-04
+3
All approaches in biomedicine souls be tested when to comes to such complex processes such as ageing - it usually takes quite a bit of time and some very convincing and reproducible experiments before just one direction can be recognised as the best approach
1 Replies
Author: Guest
Posted: 2014-08-04
+1
Yes, and it could just happen that "negligible senescence" can provide these key answers Reply
Reply
Author: Guest
Posted: 2014-08-04
+1
The inherited, genetic drivers of aging and illness are still poorly understood. But that may change in coming years. Scientists believe the sorcerer’s stone is written in our DNA, we just have to mine the code.
1 Replies
Author: Guest
Posted: 2014-08-04
+1
I believe that new and cheaper methods to sequence DNA of entire genomes are providing very important resource in many fields of biology - from evolution to ageing . However it is not easy to convert these data into information but this is coming Reply
Reply
Author: Guest
Posted: 2014-08-04
+1
Medical research has largely focused on finding genetic markers of disease. The genetics of good health are also important. As pointed out in this article, we should try to understand the mechanisms that help keep people healthy and protected from disease, and to translate key discoveries into improvements in patient care. Reply
Author: Guest
Posted: 2014-08-04
+0
Very important question but difficult to answer: Why some people live long lives without ever developing a serious disease or losing their mental faculties? Genome sequencing could give at least some answers Reply


 

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