Social Media Sidebar

Announcement

Please sign up, comment on articles and bring your friends!

Current poll

PlanetTech is asking:

What do you think about our new web site?

Love it, indeed
Really good solution
Same as old one
The old one was better
This is a new option

Quote of the day

'By far the greatest danger of Artificial Intelligence is that people conclude too early that they understand it'

 

Eliezer Yudkowsky

Antidepressants show potential for postoperative pain relief

RATE THIS! +27
Posted in Science on 30th Aug, 2014 09:40 PM by AlexMuller

After a systematic review of clinical trials based on administering antidepressants for acute and chronic postsurgical pain, researchers have concluded that more trials are needed to determine whether these drugs should be prescribed for postsurgical pain on a regular basis.

 
Dr. Ian Gilron, a professor and director of clinical pain research in the Department of Anesthesiology, and his team of seven researchers reviewed 15 trials to determine whether the use of antidepressants for pain relief post-surgery would work more effectively than painkillers such as opioids, local anesthetics, or acetaminophen. Clinical trials are often used to answer questions about the efficacy of the off-label uses of drugs. In the case of antidepressants, their effects on postsurgical pain continue to be an area of research interest.
 
“For the past 50 years, it’s been observed that antidepressants for other chronic pain conditions relieve pain independently of their effect on depression,” says Dr. Gilron, who also works as an attending anesthesiologist at Kingston General Hospital (KGH). “Even with the best available medicines, there are still many people who experience postoperative pain. Reviewing the use of antidepressants to manage this pain was definitely an opportunity to be seized.”
 
Pain around a surgical site can interfere with normal activities like walking; it can also prolong recovery from surgery. After searching through three databases of trials, first author of the paper and fifth year anesthesiology resident Karen Wong sifted through 1,350 records from three different research databases to select the 15 trials for detailed review.
 
Trials were selected for review based on a patient’s pain at rest and with movement, adverse effects of antidepressants, and other outcomes of using antidepressants for postsurgical pain. Just over half of the trials examined showed a reduction in pain after use of antidepressants.

Tags: painchronic painantidepressantshealthmedicinesurgery

Read original article » Back to category

Comments

Author: Guest
Posted: 2014-08-31
+1
Indeed, it is a great opportunity to take one type of drug that has already been developed, tested for toxicity and approved, and use it for another purpose- makes sense. However, a new benefits need to be confirmed, in this case, better than they are at the moment- further clinical trials of antidepressants as a post surgical pain release are necessary Reply


 

Recent headlines

  • Posted in Software on 2017-04-24 17:45:36
    Google Says Machine Learning Chips Make AI Faster and.....read more
    Posted in Medicine on 2017-04-24 17:37:42
    The world's first vaccine against malaria will be.....read more
    Posted in Business on 2017-04-24 17:32:06
    Apple’s New Hires Signal It May Be Looking At Satellite.....read more
    Posted in Science on 2017-04-23 16:03:05
    Google's universal quantum computer could become world's.....read more
    Posted in Medicine on 2017-04-23 15:51:27
    Anti-dementia drugs will soon start clinical trials..read more
Posted in Business on 2013-10-10 01:33
China is working towards a manned lunar mission in about.....read more
Posted in Business on 2013-10-20 07:17
Spacex says China is their main competitor for commercial.....read more
Posted in Software on 2013-10-20 06:43
Pirate Bay Browser Clocks 1,000,000 Downloads..read more
Posted in Medicine on 2013-10-10 02:10
Google reportedly investing hundreds of millions into new.....read more
Posted in Medicine on 2013-10-14 03:13
Endothelial Cells Can Repair and Regenerate Organs,.....read more
Posted in Science on 01.01.2010
Spacex says China is their main competitor for commercial.....read more
Posted in Science on 01.01.2010
Staring at Your Phone Could Be Making You Short Sighted..read more
Posted in Science on 01.01.2010
Oculus Rift virtual reality headset coming to mobile, but.....read more
Posted in Science on 01.01.2010
China is working towards a manned lunar mission in about.....read more
Posted in Science on 01.01.2010
Delivering drugs via nanoparticles to target mitochondria..read more

Recent Blog Posts

  • Posted by AlexMuller
    Intensive medical treatment can reverse type 2 diabetes..read more
    Posted by AlexMuller
    Daily consumption of tea protects the elderly from cognitive.....read more
    Posted by AlexMuller
    New analysis method of metabolites accurately predicts whether.....read more
    Posted by AlexMuller
    Unproven stem cell 'therapy' blinds three patients at Florida.....read more
    Posted by AlexMuller
    Indigenous South American group has healthiest arteries of all.....read more

Login to your Account

Login to your PlanetTech Account here

Username:
Password:
Remember me
or

Create a New Account

You just need username and password

The following errors occured:
Username:
Email:
Password:
Verify password:
Remember me