Bionic pancreas shows promise in advanced human trials
This February, we first heard about a "bionic pancreas" that could radically improve the lives of type 1 diabetes patients. At the time, multi-day trials involving groups of adult and adolescent patients were still yet to occur. Those trials have now taken place, and the results are definitely encouraging.
Being developed by scientists at Boston University and Massachusetts General Hospital, the bionic pancreas is made up of two externally-worn pumps, an app on an iPhone 4s, and a tiny sensor within a needle that's inserted under the skin.
Every five minutes, that sensor monitors the glucose levels in the surrounding tissue fluid, and sends the readings to the app. If those levels get too high or too low, the app automatically triggers one or the other of the pumps to release either insulin or its counteracting hormone, glucagon, into the bloodstream.
Ordinarily, diabetics must monitor glucose levels themselves several times a day via fingerstick blood tests. If more insulin is required, it must be either manually injected or pumped into their body.
In the tests, a group of 20 adult diabetics used the bionic pancreas for five days while conducting their usual activities in downtown Boston, plus a group of 32 adolescents also tried them out over a five-day period at a youth camp. As a control, both groups were also monitored for a five-day period while only using their regular manual insulin pumps.
The device ended up working even better than expected. The adults required 37 percent less interventions for hypoglycemia (low blood glucose), while the youth experienced an almost-twofold reduction. Additionally, the adults saw a twofold reduction in the amount of time spent in a hypoglycemic state.