Social Media Sidebar

Announcement

Please sign up, comment on articles and bring your friends!

Current poll

PlanetTech is asking:

What do you think about our new web site?

Love it, indeed
Really good solution
Same as old one
The old one was better
This is a new option

Quote of the day

People say we're running out of energy. That's only true if we stick with these old 19th century technologies. We are awash in energy from sunlight.

 

Ray Kurzweil

 

Brain disease leads to new understanding of bacterial behavior

RATE THIS! +48
Posted in Science on 9th Jul, 2016 04:11 PM by AlexMuller

Approximately 89,000 people die every year from melioidosis, an infection spread through bacteria from contaminated water and soil that can travel to the brain and spinal cord in less than 24 hours. A new study from Griffith University in Queensland, Australia discovered for the first time how the bacteria is contracted.

 

The finding could explain how other infectious bacteria make their way to the brain and spinal cord. The study, published in the journal Infection and Immunity on Tuesday, revealed the startling discovery that the bacteria Burkholderia pseudomallei enters through the nasal passage and uses the nerves in the nasal cavity as a pathway to the body's central nervous system. Researchers used mice in their study to observe the bacteria's pathway.

 
The bacteria travels through a crucial nerve connected to the nasal cavity and the brain stem called the trigeminal nerve, the largest of the 12 cranial nerves that supply feelings to the face and work as the motor nerve for functions such as chewing.
 
Researchers were able to rule out the bloodstream as a possible passageway for the bacteria by using a "capsule-deficient mutant of B. pseudomallei, which does not survive in the blood," according to the study.
 
The US Centers for Disease Control says that cases of melioidosis have been reported all over the world, but generally come from tropical and subtropical locations associated with periods of heavy rainfall. The regions with the most reported cases include Thailand, Malaysia, Singapore and Northern Australia.
 
Melioidosis has a 20 percent mortality rate in Australia and a 40 percent mortality rare in Southeast Asia. Doctors have a hard time diagnosing the disease before it reaches the brain stem because patients who contract the bacteria may not know they have it once they've been infected.
 
"You could have it and don't know it, that's scary," says Dr. James St. John, the head of Griffith University's Clem Jones Centre for Neurobiology and Stem Cell Research. "It could just be sitting there waiting for an opportune moment, or it could just be doing small incremental damage over a lifetime. You could lose the function in your brain incrementally."
 
Further study is needed to determine the full extent of the damage that the bacteria causes to the central nervous system and if other more common bacteria such as staphylococcus and acne also move to the spinal cord following infection. It could even provide new insights into the root causes of more serious diseases such as Alzheimer's.
 
A study published last May in the journal Translational Medicine by researchers at Harvard University theorized that the brain's natural defense for fighting off viruses, fungi or bacteria could be the cause of the plaque that leave pockmarks on the brain over time. 

Tags: braininfectionhealthmedicinebacteriadisease

Read original article » Back to category

Comments

Author: Guest
Posted: 2016-07-10
+1
Despite brain-blood barrier, brain is very vulnerable to infection and this study convincingly shows one of the routes, via nasal nerves
1 Replies
Author: Guest
Posted: 2016-07-10
+0
Another important question that needs to be addressed is how exactly the bacteria that enter the brain cause a disease and look foe any points that would allow intervention Reply
Reply


 

Recent headlines

  • Posted in Software on 2017-09-19 18:06:17
    China orders Bitcoin exchanges in capital city to close..read more
    Posted in Hardware on 2017-09-19 18:00:15
    LinkSpace is a Chinese startup that will try to make.....read more
    Posted in Medicine on 2017-09-19 17:54:24
    A Permanent Vaccine Against Tooth Cavity and Decay..read more
    Posted in Software on 2017-09-18 18:14:00
    China to become artificial intelligence 'world leader' by.....read more
    Posted in Science on 2017-09-18 18:10:24
    There's an Ocean Deep Inside the Earth..read more
Posted in Business on 2013-10-10 01:33
China is working towards a manned lunar mission in about.....read more
Posted in Business on 2013-10-20 07:17
Spacex says China is their main competitor for commercial.....read more
Posted in Software on 2013-10-20 06:43
Pirate Bay Browser Clocks 1,000,000 Downloads..read more
Posted in Medicine on 2013-10-10 02:10
Google reportedly investing hundreds of millions into new.....read more
Posted in Medicine on 2013-10-14 03:13
Endothelial Cells Can Repair and Regenerate Organs,.....read more
Posted in Science on 01.01.2010
Spacex says China is their main competitor for commercial.....read more
Posted in Science on 01.01.2010
Staring at Your Phone Could Be Making You Short Sighted..read more
Posted in Science on 01.01.2010
Oculus Rift virtual reality headset coming to mobile, but.....read more
Posted in Science on 01.01.2010
China is working towards a manned lunar mission in about.....read more
Posted in Science on 01.01.2010
Delivering drugs via nanoparticles to target mitochondria..read more

Recent Blog Posts

  • Posted by AlexMuller
    Scientists probe Neptune's depths to reveal secrets of icy.....read more
    Posted by AlexMuller
    New terahertz imaging approach could speed up skin cancer.....read more
    Posted by AlexMuller
    Rebutting the claim that antidepressants do not work..read more
    Posted by AlexMuller
    Artificial neural networks decode brain activity during.....read more
    Posted by AlexMuller
    Four Earth-sized planets detected orbiting the nearest.....read more

Login to your Account

Login to your PlanetTech Account here

Username:
Password:
Remember me
or

Create a New Account

You just need username and password

The following errors occured:
Username:
Email:
Password:
Verify password:
Remember me