Social Media Sidebar

Announcement

Please sign up, comment on articles and bring your friends!

Current poll

PlanetTech is asking:

What do you think about our new web site?

Love it, indeed
Really good solution
Same as old one
The old one was better
This is a new option

Quote of the day

We are all now connected by the Internet, like neurons in a giant brain.

 

Stephen Hawking

 

Children on the autistic spectrum have extra synapses in their brains

RATE THIS! +38
Posted in Science on 27th Aug, 2014 12:03 AM by AlexMuller

Children and adolescents with autism have a surplus of synapses in the brain, and this excess is due to a slowdown in a normal brain “pruning” process during development, according to a study by neuroscientists at Columbia University Medical Center (CUMC).

 
Because synapses are the points where neurons connect and communicate with each other, the excessive synapses may have profound effects on how the brain functions. The study was published in the August 21 online issue of the journal Neuron.
 
A drug that restores normal synaptic pruning can improve autistic-like behaviors in mice, the researchers found, even when the drug is given after the behaviors have appeared. “This is an important finding that could lead to a novel and much-needed therapeutic strategy for autism,” said Jeffrey Lieberman, MD, Lawrence C. Kolb Professor and Chair of Psychiatry at CUMC and director of New York State Psychiatric Institute, who was not involved in the study.
 
Although the drug, rapamycin, has side effects that may preclude its use in people with autism, “the fact that we can see changes in behavior suggests that autism may still be treatable after a child is diagnosed, if we can find a better drug,” said the study’s senior investigator, David Sulzer, PhD, professor of neurobiology in the Departments of Psychiatry, Neurology, and Pharmacology at CUMC.

Tags: brainmental healthautismneuroscience

Read original article » Back to category

Comments

Author: Guest
Posted: 2014-08-27
+3
This is probably the most hopeful finding in his field for years! However, caution. Autism is a big spectrum of related and overlapping symptoms and the question is which of those their animal model is modelling - and further, humans could be quite different in this respect anyway
2 Replies
Author: Guest
Posted: 2014-08-27
+1
Autors discuss this heterogeneity and find their approach useful: “The current view is that autism is heterogeneous, with potentially hundreds of genes that can contribute. That’s a very wide spectrum, so the goal now is to understand how those hundreds of genes cluster together into a smaller number of pathways; that will give us better clues to potential treatments” Reply
Reply
Author: Guest
Posted: 2014-08-27
+2
Not everyone agrees with this approach. This idea of artificially inducing the autophageal process on synapse-rich autistic brains in an effort to make them “normal” could turn out to be no more than a biotechnic for “dumbing down” the natural potential gifts that autistic brains may be capable of realising. And this potential should recognised and preserved!
2 Replies
Author: Guest
Posted: 2014-08-27
+1
I agree. As the products of long lines of evolutionary changes we seem to think people who think and act like us are “normal” and everyone else needs to fall into line. Children with autism might be just what society needs as we move forward.
Reply
Reply


 

Recent headlines

  • Posted in Science on 2017-08-16 23:13:20
    There’s a lot of money up for grabs if you can land.....read more
    Posted in Medicine on 2017-08-16 18:10:10
    3D printing living tissues to form living structures..read more
    Posted in Medicine on 2017-08-16 18:07:30
    algorithm can spot depression based on your Instagram posts..read more
    Posted in Business on 2017-08-16 18:03:59
    Ethereum sets new transaction record, outperforming Bitcoin..read more
    Posted in Medicine on 2017-08-15 17:58:46
    'Fat but fit' still risk heart disease..read more
Posted in Business on 2013-10-10 01:33
China is working towards a manned lunar mission in about.....read more
Posted in Business on 2013-10-20 07:17
Spacex says China is their main competitor for commercial.....read more
Posted in Software on 2013-10-20 06:43
Pirate Bay Browser Clocks 1,000,000 Downloads..read more
Posted in Medicine on 2013-10-10 02:10
Google reportedly investing hundreds of millions into new.....read more
Posted in Medicine on 2013-10-14 03:13
Endothelial Cells Can Repair and Regenerate Organs,.....read more
Posted in Science on 01.01.2010
Spacex says China is their main competitor for commercial.....read more
Posted in Science on 01.01.2010
Staring at Your Phone Could Be Making You Short Sighted..read more
Posted in Science on 01.01.2010
Oculus Rift virtual reality headset coming to mobile, but.....read more
Posted in Science on 01.01.2010
China is working towards a manned lunar mission in about.....read more
Posted in Science on 01.01.2010
Delivering drugs via nanoparticles to target mitochondria..read more

Recent Blog Posts

  • Posted by AlexMuller
    Newly discovered biomarkers may lead to promising diagnostic.....read more
    Posted by AlexMuller
    Understanding cell segregation mechanisms which help prevent.....read more
    Posted by AlexMuller
    Unique features of individual brains captured..read more
    Posted by AlexMuller
    Lutein, found in leafy greens, may counter cognitive aging..read more
    Posted by AlexMuller
    New surgical strategy offers hope for repairing spinal injuries..read more

Login to your Account

Login to your PlanetTech Account here

Username:
Password:
Remember me
or

Create a New Account

You just need username and password

The following errors occured:
Username:
Email:
Password:
Verify password:
Remember me