Social Media Sidebar

Announcement

Please sign up, comment on articles and bring your friends!

Current poll

PlanetTech is asking:

What do you think about our new web site?

Love it, indeed
Really good solution
Same as old one
The old one was better
This is a new option

Quote of the day

'By far the greatest danger of Artificial Intelligence is that people conclude too early that they understand it'

 

Eliezer Yudkowsky

Controversial Transmittable Alzheimers Theory Is Starting to Look Plausible

RATE THIS! +28
Posted in Science on 27th Jan, 2016 01:40 PM by AlexMuller

Back in September, researchers here in the UK discovered that brain disorders such as Alzheimer’s may be transmissible through certain medical procedures. Sceptical scientists urged caution, but now a different set of autopsy results have shown the same thing.

 
As reported in Nature News, the latest autopsies were performed on the brains of patients who died of Creutzfeldt–Jakob disease (CJD), a rare brain-wasting disorder. Many years earlier, these individuals had received surgical grafts of dura mater, a membrane that covers the brain and spinal cord, prepared from human cadavers. Regrettably, these grafts that were contaminated with the prion protein responsible for CJD.
 
Five of the seven brains analysed also showed signs of Alzheimer’s disease. This was odd because the individuals, age 28 to 63, were too young to have developed the amayoid plaques indicative of the neurological disorder (amyloid plaques are a misfolded protein that fuels the spread of Alzheimer’s).
 
Analysis of a control group failed to show signs of this wasting signature. This suggests that that the “seeds” of certain neurological diseases can be transmitted during certain medical procedures, or even through contaminated surgical instruments. The new report, written by researchers from Switzerland and Austria, can now be found in Swiss Medical Weekly.
 
Back in September, a different research team discovered something very similar. While performing an autopsy on eight CJD patients, University of College London researchers found that four of them exhibited similar vascular amyloid beta pathology. Alarmingly, all of these patients, most of whom were quite young when they died, caught their CJD from a growth hormone derived from the pituitary glands of human cadavers, some of which were contaminated with prions.
 
Importantly, neither study suggests that Alzheimer’s can be transmitted through normal physical contact. Also, cadaver-derived human growth hormone (HGH) isn’t used any more, as it’s been replaced by synthetics. But scientists are now seriously worried that “amyloid seeding” is actually a thing. Nature News reports:
 
[If true] it would have important clinical implications. In general surgery, for example, any amyloid-β proteins, which are very sticky, would not be routinely removed from surgical instruments; standard sterilization procedures cannot shift them.
 
“It is our job as doctors to see in advance what might become a problem in the clinic,” says neuropathologist Herbert Budka of the University Hospital Zurich, Switzerland, who is a co-author of the latest paper.
 
This theory will require more proof if it’s to be accepted by the scientific community. Both studies are purely observational, and both were performed on a limited sample of subjects. Moreover, neither study proves that the deposits of amyloid beta were actually caused by the contaminated dura mater or hormone injections.
 
But these finding, though preliminary, are nonetheless disturbing. It shows we still have lots to learn about neurodegnerative disorders and the ways in which seeds of amyloid beta proteins can be transmitted. And if this theory is ultimately proven to be true, it will put even more pressure on health care providers to provide a clean and safe environment for its patients. It’s a terrifying thought.

Tags: Alzheimer'sdementiaresearchbraindiseasecellshealthmedicine

Read original article » Back to category

Comments

Author: Guest
Posted: 2016-01-28
+1
The idea that some surgical procedures can result in generation of beta amyloid is quite unsettling, it would be quite important to know for sure as well as number of patients that could potentially be affected in this way Reply


 

Recent headlines

  • Posted in Hardware on 2017-03-29 09:24:33
    ExoMars: Mars Rover scientists to study Mawrth Vallis.....read more
    Posted in Software on 2017-03-29 09:20:25
    AI to dominate banking, says report..read more
    Posted in Business on 2017-03-29 09:15:30
    Trump signs order undoing Obama climate change policies..read more
    Posted in Hardware on 2017-03-29 09:08:41
    SpaceX launch of private citizens on a lunar orbiting.....read more
    Posted in Business on 2017-03-28 14:55:07
    Bots shift towards AI and garner $24 billion of investment..read more
Posted in Business on 2013-10-10 01:33
China is working towards a manned lunar mission in about.....read more
Posted in Business on 2013-10-20 07:17
Spacex says China is their main competitor for commercial.....read more
Posted in Software on 2013-10-20 06:43
Pirate Bay Browser Clocks 1,000,000 Downloads..read more
Posted in Medicine on 2013-10-10 02:10
Google reportedly investing hundreds of millions into new.....read more
Posted in Medicine on 2013-10-14 03:13
Endothelial Cells Can Repair and Regenerate Organs,.....read more
Posted in Science on 01.01.2010
Spacex says China is their main competitor for commercial.....read more
Posted in Science on 01.01.2010
Staring at Your Phone Could Be Making You Short Sighted..read more
Posted in Science on 01.01.2010
Oculus Rift virtual reality headset coming to mobile, but.....read more
Posted in Science on 01.01.2010
China is working towards a manned lunar mission in about.....read more
Posted in Science on 01.01.2010
Delivering drugs via nanoparticles to target mitochondria..read more

Recent Blog Posts

  • Posted by AlexMuller
    Intensive medical treatment can reverse type 2 diabetes..read more
    Posted by AlexMuller
    Daily consumption of tea protects the elderly from cognitive.....read more
    Posted by AlexMuller
    New analysis method of metabolites accurately predicts whether.....read more
    Posted by AlexMuller
    Unproven stem cell 'therapy' blinds three patients at Florida.....read more
    Posted by AlexMuller
    Indigenous South American group has healthiest arteries of all.....read more

Login to your Account

Login to your PlanetTech Account here

Username:
Password:
Remember me
or

Create a New Account

You just need username and password

The following errors occured:
Username:
Email:
Password:
Verify password:
Remember me