Social Media Sidebar


Please sign up, comment on articles and bring your friends!

Current poll

PlanetTech is asking:

What do you think about our new web site?

Love it, indeed
Really good solution
Same as old one
The old one was better
This is a new option

Quote of the day

When seen through the lens of technology, few resources are truly scarce; they’re mainly inaccessible. 


Peter Diamandis

Deep brain imaging reveals which nearly identical neurons are associated with specific behaviors

Posted in Science on 3rd Feb, 2015 02:25 PM by AlexMuller

New deep-brain imaging techniques can link the activity of individual, genetically similar neurons to particular behaviors of mice. For the first time, scientists watched as one neuron was activated when a mouse searched for food while a nearly identical neuron remained inactive.

This work, published in the journal Cell, suggests that manipulating an entire genetically defined subtype of neurons to treat a condition, such as binge-eating, might be too broad of an approach. Drug developers might have to focus on one type of cell within the subset to avoid potentially serious side effects. This study, led by Garret Stuber, PhD, assistant professor of psychiatry, is one of the first published reports using novel technologies that support the NIH BRAIN Initiative to map how individual neurons and neural circuits interact throughout the brain.
“Traditional imaging techniques wouldn’t allow us to record this kind of activity deep inside the brains of freely moving mice,” said Stuber, who is also a member of the UNC Neuroscience Center. “For the first time, we can view specific, genetically defined neurons in the lateral hypothalamus as they light up while the mice search out food, eat, and drink.” The finding suggests that targeting an entire subpopulation of brain cells to learn about their functions can be somewhat misleading.
“This is important to know because if we want to create a drug treatment for obesity, for instance, then you wouldn’t want to affect cells involved in appetite because you might affect cells involved in other aspects of motivated behavior,” said Stuber. “But if we could target only the cells involved in consumption, then maybe we could modulate only those cells without affecting motivation.”

Tags: brainneuronsneurosciencebehaviorimagingcell

Read original article » Back to category


Author: Guest
Posted: 2015-02-04
New methods that are allowing functional mapping of the brain are making enormous contribution to gain essential knowledge for new treatments - brilliant work! Reply


Recent headlines

  • Posted in Business on 2018-03-21 00:36:13
    China versus USA in AI more
    Posted in Business on 2018-03-21 00:31:37
    Anti-aging biotech Unity adds $55M as it preps more
    Posted in Software on 2018-03-19 21:43:31
    Artificial Intelligence can spot signs of Alzheimer’ more
    Posted in Business on 2018-03-19 21:36:26
    Bitcoin may not last, but blockchain could be the real more
    Posted in Medicine on 2018-03-18 20:36:22
    Study suggests our biological ageing is slowing more
Posted in Business on 2013-10-10 01:33
China is working towards a manned lunar mission in more
Posted in Business on 2013-10-20 07:17
Spacex says China is their main competitor for more
Posted in Software on 2013-10-20 06:43
Pirate Bay Browser Clocks 1,000,000 more
Posted in Medicine on 2013-10-10 02:10
Google reportedly investing hundreds of millions into more
Posted in Medicine on 2013-10-14 03:13
Endothelial Cells Can Repair and Regenerate Organs, more
Posted in Science on 01.01.2010
Spacex says China is their main competitor for more
Posted in Science on 01.01.2010
Staring at Your Phone Could Be Making You Short more
Posted in Science on 01.01.2010
Oculus Rift virtual reality headset coming to mobile, more
Posted in Science on 01.01.2010
China is working towards a manned lunar mission in more
Posted in Science on 01.01.2010
Delivering drugs via nanoparticles to target more

Recent Blog Posts

  • Posted by AlexMuller
    Martian landscapes formed from sand 'levitating' on a more
    Posted by AlexMuller
    Scientists detect comets outside our solar more
    Posted by AlexMuller
    Advanced artificial limbs mapped in the more
    Posted by AlexMuller
    Bacteria have a sense of more
    Posted by AlexMuller
    Recurrent brain cancer: New hope with phase 1 clinical more

Login to your Account

Login to your PlanetTech Account here

Remember me

Create a New Account

You just need username and password

The following errors occured:
Verify password:
Remember me