Social Media Sidebar

Announcement

Please sign up, comment on articles and bring your friends!

Current poll

PlanetTech is asking:

What do you think about our new web site?

Love it, indeed
Really good solution
Same as old one
The old one was better
This is a new option

Quote of the day

People say we're running out of energy. That's only true if we stick with these old 19th century technologies. We are awash in energy from sunlight.

 

Ray Kurzweil

 

Deep neural networks to help identify, formulate advanced antiaging supplements

RATE THIS! +43
Posted in Science on 9th Jun, 2016 11:29 AM by AlexMuller

Insilico Medicine is a big-data analytics company specializing in applying advances in deep learning to discovery of biomarkers and drugs. Life Extension, a Florida-based organization established in the early 1980s, is a dietary-supplement innovator dedicated to extending healthy human longevity.

 
Insilico Medicine will focus on applying advanced signaling pathway activation analysis techniques and deep-learning algorithms to find nutraceuticals that mimic the tissue-specific transcriptional response of many known interventions and pathways associated with health and longevity.
 
Life Extension will use this information to develop novel nutraceutical products to support health and longevity, such as “geroprotectors”, precision natural organic small-molecule formulations that slow down or even reverse age-associated conditions and damage.
 
“Senescence is accompanied by a shift in cellular signaling that initiates and promotes a system-wide degenerative condition,” William Faloon, co-founder of the Life Extension Foundation, told KurzweilAI. “By turning back ‘on’ youthful signaling pathways while suppressing those that emerge during normal maturation, we expect to gain significant control over what are now thought to be inevitable pathologies of old age.”
 
“This collaboration means a lot to our team. For many years I was buying a range of supplements from Life Extension, and saw how passionate they are about extending healthy human life and supporting cutting-edge research in the field,” said Alex Zhavoronkov, PhD, CEO of Insilico Medicine, Inc. and the chief science officer of the Biogerontology Research Foundation in the UK.
 
“Life Extension’s discovery research and product development teams have decades of experience in the pharmaceutical and nutraceutical research and have set very high standards for science-based nutraceutical discovery.”
 
Insilico Medicine scientists will present the results of this collaboration at RAADFest in San Diego in August, a longevity-focused conference.
 
Insilico Medicine scientists have recently authored key papers on applying deep-learning techniques to biomedical applications in influential peer-reviewed journals, including “Developing criteria for evaluation of geroprotectors as a key stage toward translation to the clinic,” published in Aging Cell.
 
Other papers include “Deep learning applications for predicting pharmacological properties of drugs and drug repurposing using transcriptomic data” in Molecular Pharmaceutics, a journal published by the American Chemical Society; “Applications of Deep Learning in Biomedicine“, also in Molecular Pharmaceutics; and “Deep biomarkers of human aging: Application of deep neural networks to biomarker development” in Aging, a high-impact journal in aging research.
 
“We believe that accelerating the rate of progress in novel biomarker identification, as well as precision nutrient formulation development, is critical,” said Andrew G. Swick, Ph.D., senior vice president of scientific affairs, discovery research and product development for Life Extension.
 
“Life Extension aims to improve health and human longevity by utilizing the experience of noted research scientists and engaging in academic and industry collaborations. Artificial intelligence is one of the promising areas, where years of experience in the nutraceutical industry combined with sophisticated biologically inspired algorithms and high-performance computing may produce unprecedented results.”

Tags: agingAIsoftwarehealthmedicineresearch

Read original article » Back to category

Comments

Author: Guest
Posted: 2016-06-09
+1
I am not sure that we have enough information to develop novel nutraceutical products to support health and longevity such as “geroprotectors”- further research is essential Reply
Author: Guest
Posted: 2016-06-09
+0
The scientists propose to turn back ‘on’ youthful signaling pathways while suppressing those that emerge during ageing. The problem here is that many pathways have multiple functions and effects can not be easily controlled Reply


 

Recent headlines

  • Posted in Medicine on 2017-09-24 12:24:41
    Effective help is available for migraine sufferers..read more
    Posted in Business on 2017-09-24 12:20:40
    AR startup Mira bags $1 million for Google Cardboard-like.....read more
    Posted in Medicine on 2017-09-24 12:14:44
    Alarm as 'super malaria' spreads in South East Asia..read more
    Posted in Science on 2017-09-23 08:31:24
    Fly me to the Moon: For some, lunar village takes shape..read more
    Posted in Software on 2017-09-23 08:22:48
    One year later, Microsoft AI and Research grows to 8k.....read more
Posted in Business on 2013-10-10 01:33
China is working towards a manned lunar mission in about.....read more
Posted in Business on 2013-10-20 07:17
Spacex says China is their main competitor for commercial.....read more
Posted in Software on 2013-10-20 06:43
Pirate Bay Browser Clocks 1,000,000 Downloads..read more
Posted in Medicine on 2013-10-10 02:10
Google reportedly investing hundreds of millions into new.....read more
Posted in Medicine on 2013-10-14 03:13
Endothelial Cells Can Repair and Regenerate Organs,.....read more
Posted in Science on 01.01.2010
Spacex says China is their main competitor for commercial.....read more
Posted in Science on 01.01.2010
Staring at Your Phone Could Be Making You Short Sighted..read more
Posted in Science on 01.01.2010
Oculus Rift virtual reality headset coming to mobile, but.....read more
Posted in Science on 01.01.2010
China is working towards a manned lunar mission in about.....read more
Posted in Science on 01.01.2010
Delivering drugs via nanoparticles to target mitochondria..read more

Recent Blog Posts

  • Posted by AlexMuller
    Scientists probe Neptune's depths to reveal secrets of icy.....read more
    Posted by AlexMuller
    New terahertz imaging approach could speed up skin cancer.....read more
    Posted by AlexMuller
    Rebutting the claim that antidepressants do not work..read more
    Posted by AlexMuller
    Artificial neural networks decode brain activity during.....read more
    Posted by AlexMuller
    Four Earth-sized planets detected orbiting the nearest.....read more

Login to your Account

Login to your PlanetTech Account here

Username:
Password:
Remember me
or

Create a New Account

You just need username and password

The following errors occured:
Username:
Email:
Password:
Verify password:
Remember me