Social Media Sidebar

Announcement

Please sign up, comment on articles and bring your friends!

Current poll

PlanetTech is asking:

What do you think about our new web site?

Love it, indeed
Really good solution
Same as old one
The old one was better
This is a new option

Quote of the day

We are all now connected by the Internet, like neurons in a giant brain.

 

Stephen Hawking

 

Drug protects against the effects of nuclear radiation 24 hours after exposure

RATE THIS! +38
Posted in Science on 23rd Aug, 2015 07:04 PM by AlexMuller

Researchers led by The University of Texas Medical Branch at Galveston reports a breakthrough in countering the deadly effects of radiation exposure. An injection of a regenerative peptide was shown to significantly increase survival in mice when given 24 hours after nuclear radiation exposure.

 

The study currently appears in Laboratory Investigation, a journal in the Nature Publishing group. UTMB lead author Carla Kantara, postdoctoral fellow in biochemistry and molecular biology, said that a single injection of the investigative peptide drug TP508 given 24 hours after a potentially-lethal exposure to radiation appears to significantly increase survival and delay mortality in mice by counteracting damage to the gastrointestinal system.

 

The threat of a nuclear incident, with the potential to kill or injure thousands of people, has raised global awareness about the need for medical countermeasures that can prevent radiation-induced bodily damage and keep people alive, even if given a day or more after contact with nuclear radiation.
 
Exposure to high doses of radiation triggers a number of potentially lethal effects. Among the most severe of these effects is the gastrointestinal, or GI, toxicity syndrome that is caused by radiation-induced destruction of the intestinal lining. This type of GI damage decreases the ability of the body to absorb water and causes electrolyte imbalances, bacterial infection, intestinal leakage, sepsis and death.
 
The GI toxicity syndrome is triggered by radiation-induced damage to crypt cells in the small intestines and colon that must continuously replenish in order for the GI tract to work properly. Crypt cells are especially susceptible to radiation damage and serve as an indicator of whether someone will survive after total body radiation exposure.
 
"The lack of available treatments that can effectively protect against radiation-induced damage has prompted a search for countermeasures that can minimize the effects of radiation after exposure, accelerate tissue repair in radiation-exposed individuals and increase the chances for survival following a nuclear event," said Darrell Carney, UTMB adjunct professor in biochemistry and molecular biology and CEO of Chrysalis BioTherapeutics, Inc. "Because radiation-induced damage to the intestines plays such a key role in how well a person recovers from radiation exposure, it's crucial to develop novel medications capable of preventing GI damage."

Tags: nuclearradiationdrugresearchmedicinehealth

Read original article » Back to category

Comments

Author: Guest
Posted: 2015-08-24
+0
I agree that new ways of treating GI exposed to radiation are needed and this is an intriguing option. Many questions and more research however remain Reply


 

Recent headlines

  • Posted in Software on 2017-04-30 18:12:52
    Experts Assert That AI Will Be Replacing CEOs..read more
    Posted in Science on 2017-04-30 17:58:36
    Scientists think Facebook and Elon Musk are way too.....read more
    Posted in Medicine on 2017-04-30 17:52:58
    Non-O blood group 'linked to higher heart attack risk'..read more
    Posted in Business on 2017-04-29 13:25:52
    Google Is Becoming 'A.I. First'..read more
    Posted in Science on 2017-04-29 13:18:48
    SpaceX looks to break into national security launch.....read more
Posted in Business on 2013-10-10 01:33
China is working towards a manned lunar mission in about.....read more
Posted in Business on 2013-10-20 07:17
Spacex says China is their main competitor for commercial.....read more
Posted in Software on 2013-10-20 06:43
Pirate Bay Browser Clocks 1,000,000 Downloads..read more
Posted in Medicine on 2013-10-10 02:10
Google reportedly investing hundreds of millions into new.....read more
Posted in Medicine on 2013-10-14 03:13
Endothelial Cells Can Repair and Regenerate Organs,.....read more
Posted in Science on 01.01.2010
Spacex says China is their main competitor for commercial.....read more
Posted in Science on 01.01.2010
Staring at Your Phone Could Be Making You Short Sighted..read more
Posted in Science on 01.01.2010
Oculus Rift virtual reality headset coming to mobile, but.....read more
Posted in Science on 01.01.2010
China is working towards a manned lunar mission in about.....read more
Posted in Science on 01.01.2010
Delivering drugs via nanoparticles to target mitochondria..read more

Recent Blog Posts

  • Posted by AlexMuller
    Nanoparticle vaccine shows potential as immunotherapy to fight.....read more
    Posted by AlexMuller
    Obesity is top cause of preventable life-years lost, study shows..read more
    Posted by AlexMuller
    Light can be utilized to control gene function..read more
    Posted by AlexMuller
    Brain stimulation restores memory during lapses, research shows..read more
    Posted by AlexMuller
    Wax worm caterpillar will eat plastic shopping bags: New.....read more

Login to your Account

Login to your PlanetTech Account here

Username:
Password:
Remember me
or

Create a New Account

You just need username and password

The following errors occured:
Username:
Email:
Password:
Verify password:
Remember me