Social Media Sidebar

Announcement

Please sign up, comment on articles and bring your friends!

Current poll

PlanetTech is asking:

What do you think about our new web site?

Love it, indeed
Really good solution
Same as old one
The old one was better
This is a new option

Quote of the day

We are all now connected by the Internet, like neurons in a giant brain.

 

Stephen Hawking

 

Editas will test CRISPR gene editing in humans in 2017

RATE THIS! +52
Posted in Science on 5th Nov, 2015 03:21 PM by AlexMuller

Biotechnology startup Editas Medicine intends to test a powerful new form of gene-repair in humans. Speaking this week at the EmTech conference in Massachusetts, Editas CEO Katrine Bosley said the company hopes to start a trial in 2017 to treat a rare form of blindness using CRISPR, a groundbreaking gene-editing technology.

 
If Editas’s plans move forward, the study would likely be the first to use CRISPR to edit the DNA of a person. CRISPR technology was invented three years ago but is so precise and cheap to use it has quickly spread through biology laboratories. Already, scientists have used it to generate genetically engineered monkeys, and the technique has stirred debate over whether modified humans are next.
 
Editas is one of several startups, including Intellia Therapeutics and CRISPR Therapeutics, that have plans to use the technique to correct DNA disorders that affect children and adults. Bosley said that because CRISPR can “repair broken genes” it holds promise for treating several thousand inherited disorders caused by gene mistakes, most of which, like Huntington’s disease and cystic fibrosis, have no cure.
 
Editas picked the disease in part because it is relatively easy to address with CRISPR, Bosley said. The exact gene error is known, and the eye is easy to reach with genetic treatments. “It feels fast, but we are going at the pace science allows,” she said. There are still questions about how well gene-editing will work in the retina and whether side effects could be caused by unintentional changes to DNA.
 
Editas plans to deliver the CRISPR technology as a gene therapy. The treatment will involve injecting into the retina a soup of viruses loaded with the DNA instructions needed to manufacture the components of CRISPR, including a protein that can cut a gene at a precise location. Bosley said in order to treat LCA, the company intends to delete about 1,000 DNA letters from a gene called CEP290 in a patient’s photoreceptor cells.

Tags: gene therapygeneticsbiotechnologybiologyCRISPReyevisionmedicine

Read original article » Back to category

Comments

Author: Guest
Posted: 2015-11-06
+2
It is amazing how fast gene editing is progressing. The application in research is taking off exponentially and will be soon a standard technique. Importantly, route to the clinic is also fast!
2 Replies
Author: Guest
Posted: 2015-11-06
+1
Yes, one of the fastest growing application of a new method in research and medicine with the impact comparable to PCR and next generation sequencing Reply
Author: Guest
Posted: 2015-11-06
+0
Yes, one of the fastest growing application of a new method in research and medicine with the impact comparable to PCR and next generation sequencing Reply
Reply
Author: Guest
Posted: 2015-11-06
+0
As with all new methods the real test is in the clinic and for prolonged periods of time- many things can happen that we are not able to predict based on research alone Reply


 

Recent headlines

  • Posted in Science on 2017-07-27 15:19:10
    Could 'cocktail geoengineering' save the climate?..read more
    Posted in Science on 2017-07-27 15:13:16
    Ketamine has 'truly remarkable' effect on depression..read more
    Posted in Science on 2017-07-27 14:59:50
    Renewable Energy Just Hit a Big Milestone..read more
    Posted in Medicine on 2017-07-26 17:05:11
    Eye test could help diagnose autism..read more
    Posted in Science on 2017-07-26 16:55:24
    Cognitive cross-training enhances learning, study finds..read more
Posted in Business on 2013-10-10 01:33
China is working towards a manned lunar mission in about.....read more
Posted in Business on 2013-10-20 07:17
Spacex says China is their main competitor for commercial.....read more
Posted in Software on 2013-10-20 06:43
Pirate Bay Browser Clocks 1,000,000 Downloads..read more
Posted in Medicine on 2013-10-10 02:10
Google reportedly investing hundreds of millions into new.....read more
Posted in Medicine on 2013-10-14 03:13
Endothelial Cells Can Repair and Regenerate Organs,.....read more
Posted in Science on 01.01.2010
Spacex says China is their main competitor for commercial.....read more
Posted in Science on 01.01.2010
Staring at Your Phone Could Be Making You Short Sighted..read more
Posted in Science on 01.01.2010
Oculus Rift virtual reality headset coming to mobile, but.....read more
Posted in Science on 01.01.2010
China is working towards a manned lunar mission in about.....read more
Posted in Science on 01.01.2010
Delivering drugs via nanoparticles to target mitochondria..read more

Recent Blog Posts

  • Posted by AlexMuller
    Nanoparticle vaccine shows potential as immunotherapy to fight.....read more
    Posted by AlexMuller
    Obesity is top cause of preventable life-years lost, study shows..read more
    Posted by AlexMuller
    Light can be utilized to control gene function..read more
    Posted by AlexMuller
    Brain stimulation restores memory during lapses, research shows..read more
    Posted by AlexMuller
    Wax worm caterpillar will eat plastic shopping bags: New.....read more

Login to your Account

Login to your PlanetTech Account here

Username:
Password:
Remember me
or

Create a New Account

You just need username and password

The following errors occured:
Username:
Email:
Password:
Verify password:
Remember me