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Exercise may protect against neurodegenerative diseases

RATE THIS! +43
Posted in Science on 21st Nov, 2015 12:09 AM by AlexMuller

Exercise may protect aging brains against the neurodegenerative diseases resulting from energy-depleting stress caused by neurotoxins and other factors, according to researchers at the National Institute on Aging Intramural Research Program and Johns Hopkins University School of Medicine.

 
They found that running-wheel exercise increased the amount of SIRT3 in neurons of normal mice and protected them against degeneration.
 
However, mice models genetically modified to not produce SIRT3 became highly sensitive to stress when exposed to neurotoxins that cause neurodegeneration and epileptic seizures, and running failed to protect the neurons. In that case, neurons could be protected against stress by a gene-therapy technology to increase levels of SIRT3 in neurons, they found.
 
These findings suggest that bolstering mitochondrial function and stress resistance by increasing SIRT3 levels, either by exercise or gene therapy, may protect against age-related cognitive decline and brain diseases, the researchers say.

Tags: brainagingexerciseresearchhealthmedicineneuroscience

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Comments

Author: Guest
Posted: 2015-11-21
+2
Exercises, we have been told again and again, are good for our health regardless of any specific problem, or health condition… So regardless whether this connection if confirmed, exercises should be taken seriously
1 Replies
Author: Guest
Posted: 2015-11-21
+1
Sure, plenty of opportunities for outdoors, gym or swimming pool..... Reply
Reply


 

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