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Fear suppressing neurons found

RATE THIS! +37
Posted in Science on 21st Feb, 2014 01:50 AM by AlexMuller

Scientists have found neurons that prevent mice from forming fearful memories in an area of the brain called the hippocampus. These inhibitory neurons ensure that a neutral memory of a context or location is not contaminated by an unpleasant event occurring at the same time. The work could one day help better understand conditions such as PTSD.

 
Attila Losonczy, from Columbia University in New York and colleagues, were interested in how the hippocampus stores memories of a particular context and then separates this memory from a fearful event.
 
When looking at individual neurons in the brains of mice, they found inhibitory cells - called interneurons - were crucial for fear memory formation to travel to the correct part of the brain.
 
"These cells are activated by the unpleasant salient event and they act somewhat like a filter. They may function to block out unwanted information related to this strong, salient event," Dr Losonczy told the BBC's Science in Action programme.

Tags: brainneuronsneurosciencefearPTSD

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Comments

Author: Guest
Posted: 2014-02-21
+1
So, it would be good to know if function of these cells is related to any neuronal disorder and would it be possible to use this knowledge for treatmen
4 Replies
Author: Guest
Posted: 2014-02-21
+2
Yes, they describe in the article that understanding how context and fear are learned and the specific neurons involved, could help scientists better help people with conditions like anxiety and post-traumatic stress disorders.
2 Replies
Author: Guest
Posted: 2014-02-21
+2
The idea of scientists manipulating memory does, naturally, sound a bit creepy. But it also points to some possible good: treatment for millions of people tormented by real memories. Reply
Reply
Author: Guest
Posted: 2014-02-21
+3
It remains a great hope that if we could understand exactly what happens on a molecular level during memory creation, perhaps we could find a solution to brain diseases Reply
Reply
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Author: Guest
Posted: 2016-12-26
+0
Hats off to whoveer wrote this up and posted it. Reply


 

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