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Growing brains in the lab

RATE THIS! +38
Posted in Science on 9th Feb, 2014 01:29 AM by AlexMuller

During development, the nervous system forms as a flat sheet called the neuroepithelium on the outer layer of the embryo. This sheet eventually folds in on itself to form a neural tube that gives rise to the brain and spinal cord, a process that involves the proliferation and migration of immature nerve cells to form the brain at one end and the spinal cord at the other.

 

Yoshiki Sasai, Taisuke Kadoshima and colleagues from the RIKEN Center for Developmental Biology have now shown that human embryonic stem (ES) cells can spontaneously organize into the cerebral cortical tissue that forms at the front, or ‘brain’ end, of the developing neural tube1. 

 
Sasai and his colleagues previously developed a novel cell culture technique that involves growing ES cells in suspension, and have shown that these cells can self-organize into complex three-dimensional structures.
 
They have already used this method to grow pieces of cerebral cortex and embryonic eyes from mouse ES cells. And more recently, they have shown that human ES cells can also organize into embryonic eyes containing retinal tissue and light-sensitive cells.

Tags: brainstem cellsregenerative medicinemedicinehealth

Read original article » Back to category

Comments

Author: Guest
Posted: 2014-02-09
+2
Growing brain in the lab is an important goal and many advances are making this possibility more and more likely- this is one of the steps that will be helpful
4 Replies
Author: Guest
Posted: 2014-02-09
+1
It would be great to see this go further towards medical applications. Efficient generation of cortical tissues could provide a valuable resource of functional neurons and tissues for this purpose Reply
Author: Guest
Posted: 2014-02-09
+0
It’s an exciting endpoint, but there are still major hurdles to clear before we get there. Reply
Reply
Author: Guest
Posted: 2014-02-09
+3
Stem cell research is looking is looking more promising recently. Since the development of pluripotent stem cells in 2006, scientists have managed to use stem cells like seeds to grow a wide range of tissues and rudimentary organs. Reply
Author: Guest
Posted: 2014-02-09
+0
Recently, scientists have been able to successfully print new eye cells that could be used to treat sight loss. This seems to be the way to go! Reply
Author: Guest
Posted: 2014-02-10
+0
Growing brain in the lab is an important goal and many advances are making this possibility more and more likely- this is one of the steps that will be helpful Reply
Author: Guest
Posted: 2016-05-06
+0
Weeeee, what a quick and easy souloitn. Reply


 

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