Social Media Sidebar

Announcement

Please sign up, comment on articles and bring your friends!

Current poll

PlanetTech is asking:

What do you think about our new web site?

Love it, indeed
Really good solution
Same as old one
The old one was better
This is a new option

Quote of the day

We are all now connected by the Internet, like neurons in a giant brain.

 

Stephen Hawking

 

HIV vaccine approach nears human trial

RATE THIS! +44
Posted in Science on 21st Jun, 2015 11:30 PM by AlexMuller

For decades, scientists have struggled to develop vaccines to stop the spread of HIV. And for decades, the vaccines have failed. HIV mutates at a ferocious pace, outrunning the immune system’s antibodies. Studies demonstrate that the immune system can be accelerated so it’s primed and ready to block HIV infection.

 
The studies describe a multi-pronged approach to an HIV vaccine, each one demonstrating a component of the process. Assembling all these components into a vaccine for humans is the final step. Testing could take place in about two years, the scientists say. The scientists, from The Scripps Research Institute, Harvard, MIT and other institutions have mapped out each step and shown in animal models that they work.
 
Three studies representing aspects of the research were released; two in the journal Science and the third in Cell. One study in Science indicates it is possible to trigger the antibody system, using an engineered molecule that mimics a vulnerable region of HIV, to make early versions of broadly neutralizing antibodies. The scientists say the primed immune system can then be successively exposed to substances that mimic aspects of HIV, to make more mature versions of these antibodies.
 
A separate study in Cell showed how the use of a different engineered molecule could complete the final stage of the maturation process to protective antibodies. Finally, a third study also in Science showed that the latter engineered molecule behaved well in vaccination of rabbits.
 
The research’s leaders include TSRI colleagues Dennis Burton, David Nemazee and William Schief. The scientists say they’re excited about the results. “It works much better than we expected,” Nemazee said. “So we’re quite positive now about trying something more complicated, like a human.”
 
While the results are strong enough to warrant human testing, many more hurdles lie ahead, said Anthony S. Fauci, director of the National Institute of Allergy and Infectious Diseases.

Tags: vaccinehealthHIVinfectionvirusresearchimmune system

Read original article » Back to category

Comments

Author: Guest
Posted: 2015-06-22
+2
Very challenging task - if vaccine for HIV can be produced, this could provide a more general approach to deal with other viruses with high frequency mutations Reply


 

Recent headlines

  • Posted in Software on 2017-06-23 12:32:59
    Google’s AI subsidiary DeepMind is partnering with.....read more
    Posted in Science on 2017-06-23 12:40:53
    Likely Mars sized planet at two times the distance to.....read more
    Posted in Science on 2017-06-23 12:14:38
    Queen's Speech: Plan aims to secure space sector..read more
    Posted in Hardware on 2017-06-22 04:47:33
    Google can turn an ordinary PC into a deep learning machine..read more
    Posted in Science on 2017-06-22 04:38:36
    Musk Wants SpaceX’s Trips To Mars To Be Like Riding.....read more
Posted in Business on 2013-10-10 01:33
China is working towards a manned lunar mission in about.....read more
Posted in Business on 2013-10-20 07:17
Spacex says China is their main competitor for commercial.....read more
Posted in Software on 2013-10-20 06:43
Pirate Bay Browser Clocks 1,000,000 Downloads..read more
Posted in Medicine on 2013-10-10 02:10
Google reportedly investing hundreds of millions into new.....read more
Posted in Medicine on 2013-10-14 03:13
Endothelial Cells Can Repair and Regenerate Organs,.....read more
Posted in Science on 01.01.2010
Spacex says China is their main competitor for commercial.....read more
Posted in Science on 01.01.2010
Staring at Your Phone Could Be Making You Short Sighted..read more
Posted in Science on 01.01.2010
Oculus Rift virtual reality headset coming to mobile, but.....read more
Posted in Science on 01.01.2010
China is working towards a manned lunar mission in about.....read more
Posted in Science on 01.01.2010
Delivering drugs via nanoparticles to target mitochondria..read more

Recent Blog Posts

  • Posted by AlexMuller
    Nanoparticle vaccine shows potential as immunotherapy to fight.....read more
    Posted by AlexMuller
    Obesity is top cause of preventable life-years lost, study shows..read more
    Posted by AlexMuller
    Light can be utilized to control gene function..read more
    Posted by AlexMuller
    Brain stimulation restores memory during lapses, research shows..read more
    Posted by AlexMuller
    Wax worm caterpillar will eat plastic shopping bags: New.....read more

Login to your Account

Login to your PlanetTech Account here

Username:
Password:
Remember me
or

Create a New Account

You just need username and password

The following errors occured:
Username:
Email:
Password:
Verify password:
Remember me