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How to generate new neurons in brains, spinal cords of living adult mammals

RATE THIS! +21
Posted in Science on 4th Mar, 2014 11:30 PM by AlexMuller

UT Southwestern Medical Center researchers have created new nerve cells in the brains and spinal cords of living mammals without the need for stem cell transplants to replenish lost cells. This new research indicates it may be possible to regenerate neurons to repair traumatic brain injury or spinal cord damage.

 
Spinal cord injuries can lead to an irreversible loss of neurons, and along with scarring, can ultimately lead to impaired motor and sensory functions. Scientists are hopeful that regenerating cells can be an avenue to repair damage, but adult spinal cords have limited ability to produce new neurons.
 
Biomedical scientists have transplanted stem cells to replace neurons, but have faced other hurdles, underscoring the need for new methods of replenishing lost cells.
 
However, the researchers stressed that it is too soon to know whether the neurons created in these initial studies resulted in any functional improvements, a goal for future research.

Tags: brainneuronsneurosciencestem cellsregenerative medicine

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Comments

Author: Guest
Posted: 2014-03-05
+3
There is a great need to understand better neuronal function and regenerative potential and a number of approaches have been used to address this problem. This is not easy- here is another potential way, we have to see....
1 Replies
Author: Guest
Posted: 2014-03-05
+0
To me, this sounds like very promising work - hopefully, they will continue to progress toward their goals in cellular reprogramming Reply
Reply
Author: Guest
Posted: 2014-03-05
+3
Earlier, reprogramming mature astrocytes to become functional neurons, without the need of cell transplantation, was a significant achievement. This study did something similar in the spine, turning scar-forming astrocytes into neurons- promising
1 Replies
Author: Guest
Posted: 2014-03-05
+1
Indeed, neuronal loss and glial scar formation result in persistent neurological dysfunction. Cellular regeneration could be an ideal approach to replenish the lost cells and repair the damage. This is a good attempt to do just that Reply
Reply
Author: Guest
Posted: 2014-03-05
+0
Regenerative medicine is the key. The future of medicine lies in understanding how the body creates itself out of a single cell and the mechanisms by which it renews itself throughout life. Reply


 

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