Social Media Sidebar

Announcement

Please sign up, comment on articles and bring your friends!

Current poll

PlanetTech is asking:

What do you think about our new web site?

Love it, indeed
Really good solution
Same as old one
The old one was better
This is a new option

Quote of the day

'By far the greatest danger of Artificial Intelligence is that people conclude too early that they understand it'

 

Eliezer Yudkowsky

Human Brain Atlas Updated with Unprecedented Resolution

RATE THIS! +45
Posted in Science on 29th Sep, 2016 04:58 PM by AlexMuller

Researchers at the Allen Brain Institute, have developed the first whole human brain map at cellular resolution. It combines neuroimaging and comprehensive mapping of brain regions. This digital atlas will allows researchers to investigate the structural basis of brain function at a resolution never possible before.

 
The Allen Human Brain Atlas is a unique multi-modal atlas that maps gene expression across the human brain. The model integrates anatomic and genomic information, available data modalities include magnetic resonance imaging (MRI), diffusion tensor imaging (DTI), histology, and gene expression data derived from both microarray and in situ hybridization (ISH) approaches.
 
Some of the key features include an "all genes, all structures" microarray survey spatially mapped to the MRI, ISH cellular resolution image data for selected genes in specific brain regions, and an annotated human brain atlas guide.
 
Now with the latest updates to the Human Brain Atlas, users can navigate the brain as easily as using Google Maps. The work was published recently in The Journal of Comparative Neurology.
 
“Essentially what we were trying to do is to create a new reference standard for a very fine anatomical structural map of the complete human brain,” says Ed Lein, principal investigator on the project. “It may seem a little bit odd, but actually we are a bit lacking in types of basic reference materials for mapping the human brain that we have in other organisms like mouse or like monkey, and that is in large part because of the enormous size and complexity of the human brain.”
 
The project, which has already been running for five years, focused on a single healthy postmortem brain from a 34-year-old woman. The research team took a complete scan of the organ, which allowed them to capture both overall brain structure and the connectivity of brain fibers.
 
The researchers next sliced the brain into 2,716 very thin sections for fine-scale, cellular analysis.
 
The key step in creating a complete brain atlas was combining broad-scale, high-resolution brain imaging data with detailed cellular-level mapping, which the researchers then annotated with the brain structures they identified. This work is now publically available as the Allen Human Brain Atlas.
 
"Because of the labor intensiveness of doing this, it always lives in the scale of a single brain,” Lein says, “and you really go to town in trying to understand everything you can about that one individual."
 
Other researchers argue that the work is too discrete, being from one subject, and that it will be inconclusive to make any broad ranging neuroscience observations from the data.
 
A different map of the brain was published earlier this year by the Human Connectome Project. The main difference is the Allen study used only one brain, while the Human Connectome Project mapped 210 brains.
 
In spite of the critics,  the effort marks a marked advance in our understanding of brain anatomy. “There simply hasn't been a complete map of the human brain as a reference piece of material for anyone studying any part of the brain,” Lein says, “and this is a completely essential part of doing research.”

Tags: brainneuroscienceanatomybiologyresearchhealthmedicine

Read original article » Back to category

Comments

Author: Guest
Posted: 2016-09-30
+2
This is a significant step in mapping brain and its functions, it is expected that more information will be added and more brains compared
1 Replies
Author: Guest
Posted: 2016-09-30
+0
Yes, I agree with the researchers. There simply hasn't been a complete map of the human brain as a reference piece of material for anyone studying any part of the brain. Reply
Reply


 

Recent headlines

  • Posted in Business on 2017-03-26 19:56:28
    The U.S. will be hit worse by job automation than other.....read more
    Posted in Business on 2017-03-26 19:49:51
    Elon Musk says Tesla will start taking orders for Solar.....read more
    Posted in Science on 2017-03-26 19:39:27
    Impact crater linked to Martian tsunamis..read more
    Posted in Software on 2017-03-25 14:13:38
    Google Develops A Deep Learning Machine That Could Learn.....read more
    Posted in Medicine on 2017-03-25 14:26:25
    Google’s Calico partners with new biotech firm to.....read more
Posted in Business on 2013-10-10 01:33
China is working towards a manned lunar mission in about.....read more
Posted in Business on 2013-10-20 07:17
Spacex says China is their main competitor for commercial.....read more
Posted in Software on 2013-10-20 06:43
Pirate Bay Browser Clocks 1,000,000 Downloads..read more
Posted in Medicine on 2013-10-10 02:10
Google reportedly investing hundreds of millions into new.....read more
Posted in Medicine on 2013-10-14 03:13
Endothelial Cells Can Repair and Regenerate Organs,.....read more
Posted in Science on 01.01.2010
Spacex says China is their main competitor for commercial.....read more
Posted in Science on 01.01.2010
Staring at Your Phone Could Be Making You Short Sighted..read more
Posted in Science on 01.01.2010
Oculus Rift virtual reality headset coming to mobile, but.....read more
Posted in Science on 01.01.2010
China is working towards a manned lunar mission in about.....read more
Posted in Science on 01.01.2010
Delivering drugs via nanoparticles to target mitochondria..read more

Recent Blog Posts

  • Posted by AlexMuller
    Intensive medical treatment can reverse type 2 diabetes..read more
    Posted by AlexMuller
    Daily consumption of tea protects the elderly from cognitive.....read more
    Posted by AlexMuller
    New analysis method of metabolites accurately predicts whether.....read more
    Posted by AlexMuller
    Unproven stem cell 'therapy' blinds three patients at Florida.....read more
    Posted by AlexMuller
    Indigenous South American group has healthiest arteries of all.....read more

Login to your Account

Login to your PlanetTech Account here

Username:
Password:
Remember me
or

Create a New Account

You just need username and password

The following errors occured:
Username:
Email:
Password:
Verify password:
Remember me