Social Media Sidebar

Announcement

Please sign up, comment on articles and bring your friends!

Current poll

PlanetTech is asking:

What do you think about our new web site?

Love it, indeed
Really good solution
Same as old one
The old one was better
This is a new option

Quote of the day

'By far the greatest danger of Artificial Intelligence is that people conclude too early that they understand it'

 

Eliezer Yudkowsky

Human Clinical Trials of the Anti-Aging Compound NMN to Start in Japan

RATE THIS! +55
Posted in Science on 27th Jun, 2016 03:11 PM by AlexMuller
Researchers at Keio University in Japan and Washington University in St. Louis are planning to begin a joint clinical study in Japan to test in humans the safety and effectiveness of a compound that is on the verge of being a proven to reverse the effects of aging. The study is to begin as early as next month.
 
David Sinclair was formerly associated with research of the compound, nicotinamide mononucleotide, or NMN.  Sinclair has previously said the compound could lead to breakthroughs that could be used to develop drugs to restore youthfulness in human cells.
 
NMN is a chemical compound produced within the bodies of many living things, including people. NMN is also contained in food products. An experiment using mice is gradually showing that this compound activates sirtuin, whose functions are weakened due to aging, improving such things as symptoms of diabetes
 
Now, Keio University's Research Ethics Committee will check the appropriateness of the plan and other factors. If approved, researchers plan to begin giving the NMN to about 10 healthy people to confirm its safety. They will then examine whether NMN can improve functions of the human body.
 
A research group including Professor Shinichiro Imai of Washington University, a gerontology expert, has confirmed that NMN activates sirtuin. An experiment giving NMN to mice found that the compound can reverse age-linked declines in metabolism and eyesight.
 
Imai has been studying molecular mechanisms of mammalian aging and longevity at cellular and organismal levels for decades and making significant contributions to the field of aging research.
 
The study is planned to be conducted by researchers including Imai and Keio University, using NMN made by a Japanese producer. The central government has decided to provide full-fledged support for anti-aging studies from next fiscal year, and is also paying attention to this clinical study.
 
"We've confirmed a remarkable effect in the experiment using mice, but it's not clear yet how much [the compound] will affect humans," Imai said. "We'll carefully conduct the study, which I hope will result in important findings originating in Japan."

Tags: aginganti-aginglife extensionbiologymedicineresearchbiotechnology

Read original article » Back to category

Comments

Author: Guest
Posted: 2016-06-28
+1
It would be great if NMN can reverse ageing in humans and to find this out clinical trials are absolutely necessary, it is good news that this is the next step Reply
Author: Guest
Posted: 2016-06-28
+0
Considering that age associated diseases are very difficult to treat and that world population is on average older every year, finding out how to revert or slow down ageing is going to have a huge impact Reply


 

Recent headlines

  • Posted in Software on 2017-04-24 17:45:36
    Google Says Machine Learning Chips Make AI Faster and.....read more
    Posted in Medicine on 2017-04-24 17:37:42
    The world's first vaccine against malaria will be.....read more
    Posted in Business on 2017-04-24 17:32:06
    Appleā€™s New Hires Signal It May Be Looking At Satellite.....read more
    Posted in Science on 2017-04-23 16:03:05
    Google's universal quantum computer could become world's.....read more
    Posted in Medicine on 2017-04-23 15:51:27
    Anti-dementia drugs will soon start clinical trials..read more
Posted in Business on 2013-10-10 01:33
China is working towards a manned lunar mission in about.....read more
Posted in Business on 2013-10-20 07:17
Spacex says China is their main competitor for commercial.....read more
Posted in Software on 2013-10-20 06:43
Pirate Bay Browser Clocks 1,000,000 Downloads..read more
Posted in Medicine on 2013-10-10 02:10
Google reportedly investing hundreds of millions into new.....read more
Posted in Medicine on 2013-10-14 03:13
Endothelial Cells Can Repair and Regenerate Organs,.....read more
Posted in Science on 01.01.2010
Spacex says China is their main competitor for commercial.....read more
Posted in Science on 01.01.2010
Staring at Your Phone Could Be Making You Short Sighted..read more
Posted in Science on 01.01.2010
Oculus Rift virtual reality headset coming to mobile, but.....read more
Posted in Science on 01.01.2010
China is working towards a manned lunar mission in about.....read more
Posted in Science on 01.01.2010
Delivering drugs via nanoparticles to target mitochondria..read more

Recent Blog Posts

  • Posted by AlexMuller
    Intensive medical treatment can reverse type 2 diabetes..read more
    Posted by AlexMuller
    Daily consumption of tea protects the elderly from cognitive.....read more
    Posted by AlexMuller
    New analysis method of metabolites accurately predicts whether.....read more
    Posted by AlexMuller
    Unproven stem cell 'therapy' blinds three patients at Florida.....read more
    Posted by AlexMuller
    Indigenous South American group has healthiest arteries of all.....read more

Login to your Account

Login to your PlanetTech Account here

Username:
Password:
Remember me
or

Create a New Account

You just need username and password

The following errors occured:
Username:
Email:
Password:
Verify password:
Remember me