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Light shed on how genes shape face

RATE THIS! +47
Posted in Science on 28th Oct, 2013 12:28 AM by AlexMuller

Scientists are starting to understand why one person's face can look so different from another's. Working on mice, researchers have identified thousands of small regions of DNA that influence the way facial features develop. The study also shows that tweaks to genetic material can subtly alter face shape.

 
The findings, published in Science, could also help researchers to learn how facial birth defects arise. The researchers said that although the work was carried out on animals, the human face was likely to develop in the same way. Professor Axel Visel, from the Joint Genome Institute at the Lawrence Berkeley National Laboratory in California, told BBC News: "We're trying to find out how these instructions for building the human face are embedded in human DNA.
 
"Somewhere in there there must be that blueprint that defines what our face looks like."
 
The international team has found more than 4,000 "enhancers" in the mouse genome that appear to play a role in facial appearance. These short stretches of DNA act like switches, turning genes on and off. And for 200 of these, the researchers have identified how and where they work in developing mice.
 
Prof Visel said: "In the mouse embryos we can see where exactly, as the face develops, this switch turns on the gene that it controls."

Tags: facial featuresDNAgenes

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Comments

Author: Guest
Posted: 2013-10-28
+1
It is hard for me to process that there is an international team working on this project and that they have found over 4,000 "enhancers" in the mouse genome Reply
Author: Guest
Posted: 2013-10-28
+1
So they have apparently narrowed these to 200, of which the researchers have identified how and where they work in developing mice. Reply
Author: Guest
Posted: 2013-10-28
+1
Yeah scientists, they are starting to understand why one person's face can look so different from another's. This is a novel thing to figure out and oh, how important. Reply
Author: Guest
Posted: 2013-11-26
+0
ブックサーフィン「死」と向き合い考える 由紀私はどんなふうに死ぬんだろう。 神奈川県足柄上郡中井町で売買・賃貸物件を探す中井町は、神奈川県の南西部に位置する人口約10,300人の緑豊かな町です。 この理由は、すべてのバッグが人のプロ職人に作られているということです。 受注受付時に送料を訂正してメー%8 Reply


 

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