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Lost sleep leads to loss of brain cells, study suggests

RATE THIS! +38
Posted in Science on 20th Mar, 2014 04:19 AM by AlexMuller

Sleep loss may be more serious than previously thought, causing a permanent loss of brain cells, research suggests. In mice, prolonged lack of sleep led to 25% of certain brain cells dying, according to a study in The Journal of Neuroscience. If the same is true in humans, it may be futile to try to catch up on missed sleep, say US scientists.

 
They think it may one day be possible to develop a drug to protect the brain from the side-effects of lost sleep. The study, published in The Journal of Neuroscience, looked at lab mice that were kept awake to replicate the kind of sleep loss common in modern life, through night shifts or long hours in the office.
 
A team at the University of Pennsylvania School of Medicine studied certain brain cells which are involved in keeping the brain alert. After several days of sleep patterns similar to those followed by night workers - three days of night shifts with only four to five hours sleep in 24 hours - the mice lost 25% of the brain cells, in part of the brain stem.
 
The researchers say this is the first evidence that sleep loss can lead to a loss of brain cells. But they add that more work needs to be done to find out if people who miss out on sleep might also be at risk of permanent damage. Prof Sigrid Veasey of the Center for Sleep and Circadian Neurobiology, told BBC News: "We now have evidence that sleep loss can lead to irreversible injury.

Tags: brainsleephealthneuroscience

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Comments

Author: Guest
Posted: 2014-03-20
+3
The findings that the lack of sleep can " kill" brain cells, if confirmed, could be very significant warning - it is already known that the length of sleep is essential for proper brain functions
2 Replies
Author: Guest
Posted: 2014-03-20
+3
It is interesting that they think it may one day be possible to develop a drug to protect the brain from the side-effects of lost sleep. Long-term ambition, by we have to see Reply
Reply
Author: Guest
Posted: 2014-03-20
+3
Researchers draw parallels with night shift work in humans and suggest how chronic sleep deprivation could adversely affect not only our physical, but also our mental health. Many effects on mental health have been described before, notably depression
3 Replies
Author: Guest
Posted: 2014-03-20
+2
Yes, there are many data about harm from short sleep. Results suggest sleeping six hours or less per night increases the risk for major depression.
2 Replies
Author: Guest
Posted: 2014-03-20
+0
Insomnia is a huge problem. Exhaustion due to poor sleep is linked to motor vehicle crashes, industrial disasters, and medical and other occupational errors with an enormous costs in lost productivity. Tackling this is important! Reply
Reply
Reply
Author: Guest
Posted: 2014-03-20
+1
Sleep problems are becoming more common. According to The Sleep Foundation about 70% of Americans have sleep problems, and 40 % don’t get the recommended seven hours of sleep a night. They believe that in part this is due to working more at home and using that time to do work at odd hours. Reply
Author: Guest
Posted: 2016-05-06
+0
Detyirahdon is the route cause of many illnesses from high blood pressure to migraines. You can read more about how dehydration causes disease in the series of articles I wrote on the subject called “Hydrate Or Die” you can read part one by clicking here Reply


 

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