Social Media Sidebar

Announcement

Please sign up, comment on articles and bring your friends!

Current poll

PlanetTech is asking:

What do you think about our new web site?

Love it, indeed
Really good solution
Same as old one
The old one was better
This is a new option

Quote of the day

When seen through the lens of technology, few resources are truly scarce; they’re mainly inaccessible. 

 

Peter Diamandis

Mitochondria can trigger cell aging, researchers discover

RATE THIS! +48
Posted in Science on 7th Feb, 2016 11:06 PM by AlexMuller

An international team of scientists led by Joao Passos at Newcastle University has for the first time shown that mitochondria (the “batteries” of the cells) are major triggers for aging, and eliminating them upon the induction of senescence prevents senescence in the aging mouse liver. This could lead to new therapies to combat age related disease.

 
As we grow old, cells in our bodies accumulate different types of damage and have increased inflammation, factors that are thought to contribute to the aging process.
 
As described Feb. 4 in an open-access paper in the EMBO Journal, the team carried out a series of genetic experiments involving human cells grown in the laboratory and succeeded in eliminating the majority, if not all, the mitochondria from aging cells.
 
Cells can normally eliminate faulty mitochondria by a process called mitophagy. The scientists were able to “trick” the cells into inducing this process in a grand scale, until all the mitochondria within the cells were physically removed.
 
To their surprise, they observed that the aging cells, after losing their mitochondria, showed characteristics similar to younger cells, that is, they became rejuvenated. The levels of inflammatory molecules, oxygen free radicals and expression of genes, which are among the makers of cellular aging, dropped to the level that would be expected in younger cells.
 
“This is a very exciting and surprising discovery,” said Passos. “We already had some clues that mitochondria played a role in the aging of cells, but scientists around the world have struggled to understand exactly how and to what extent these were involved.”
 
The team, involving other universities in the UK and the U.S., also deciphered a new mechanism by which mitochondria contribute to aging: mitochondrial biogenesis, the complex process by which mitochondria replicate themselves, is a major driver of cellular aging.

Tags: cellsbiologymitochondriaagingresearch

Read original article » Back to category

Comments

Author: Guest
Posted: 2016-02-08
+1
Mitochondria are linked to many different cellular functions and this new discovery in their role in ageing could help to find out more about such links Reply
Author: Guest
Posted: 2016-05-07
+0
Great hammer of Thor, that is pollefuwry helpful! Reply


 

Recent headlines

  • Posted in Science on 2018-01-17 21:36:07
    SpaceX crushing ULA in terms of value for US taxpayer.....read more
    Posted in Hardware on 2018-01-17 21:23:59
    Can Molten Salt Make 24-Hour Solar Energy Possible?..read more
    Posted in Business on 2018-01-17 21:20:13
    2018 could bring the IPOs that tech has been promised for.....read more
    Posted in Medicine on 2018-01-16 20:00:18
    Is anxiety a strong early indicator of Alzheimer's disease?..read more
    Posted in Medicine on 2018-01-16 19:26:56
    Can psychedelic drugs such as magic mushroom 'reconnect'.....read more
Posted in Business on 2013-10-10 01:33
China is working towards a manned lunar mission in about.....read more
Posted in Business on 2013-10-20 07:17
Spacex says China is their main competitor for commercial.....read more
Posted in Software on 2013-10-20 06:43
Pirate Bay Browser Clocks 1,000,000 Downloads..read more
Posted in Medicine on 2013-10-10 02:10
Google reportedly investing hundreds of millions into new.....read more
Posted in Medicine on 2013-10-14 03:13
Endothelial Cells Can Repair and Regenerate Organs,.....read more
Posted in Science on 01.01.2010
Spacex says China is their main competitor for commercial.....read more
Posted in Science on 01.01.2010
Staring at Your Phone Could Be Making You Short Sighted..read more
Posted in Science on 01.01.2010
Oculus Rift virtual reality headset coming to mobile, but.....read more
Posted in Science on 01.01.2010
China is working towards a manned lunar mission in about.....read more
Posted in Science on 01.01.2010
Delivering drugs via nanoparticles to target mitochondria..read more

Recent Blog Posts

  • Posted by AlexMuller
    Martian landscapes formed from sand 'levitating' on a little.....read more
    Posted by AlexMuller
    Scientists detect comets outside our solar system..read more
    Posted by AlexMuller
    Advanced artificial limbs mapped in the brain..read more
    Posted by AlexMuller
    Bacteria have a sense of touch..read more
    Posted by AlexMuller
    Recurrent brain cancer: New hope with phase 1 clinical trial.....read more

Login to your Account

Login to your PlanetTech Account here

Username:
Password:
Remember me
or

Create a New Account

You just need username and password

The following errors occured:
Username:
Email:
Password:
Verify password:
Remember me