Social Media Sidebar

Announcement

Please sign up, comment on articles and bring your friends!

Current poll

PlanetTech is asking:

What do you think about our new web site?

Love it, indeed
Really good solution
Same as old one
The old one was better
This is a new option

Quote of the day

'By far the greatest danger of Artificial Intelligence is that people conclude too early that they understand it'

 

Eliezer Yudkowsky

nanoparticle halts multiple sclerosis, diabetes, allergies

RATE THIS! +6
Posted in Science on 20th Nov, 2012 08:02 PM by AlexMuller

Northwestern Medicine researchers have developed a biodegradable nanoparticle  that stealthily delivers an antigen that tricks the immune system into stopping its attack on myelin and haltd a model of relapsing remitting multiple sclerosis (MS) in mice, according to new research.

 

The nanoparticles can also be applied to other immune-mediated diseases, including Type 1 diabetes, food allergies, and asthma.

 

In MS, the immune system attacks the myelin membrane that insulates nerves cells in the brain, spinal cord, and optic nerve. When the insulation is destroyed, electrical signals can’t be effectively conducted, resulting in symptoms that range from mild limb numbness to paralysis or blindness. About 80 percent of MS patients are diagnosed with the relapsing remitting form of the disease.

 

The nanoparticles do not suppress the entire immune system, as do current therapies for MS, which make patients more susceptible to everyday infections and higher rates of cancer. Rather, when the nanoparticles are attached to myelin antigens and injected into the mice, the immune system is reset to normal. The immune system stops recognizing myelin as an alien invader and halts its attack on it.

 

“This is a highly significant breakthrough in translational immunotherapy,” said Stephen Miller, a corresponding author of the study and the Judy Gugenheim Research Professor of Microbiology-Immunology at Northwestern Feinberg School of Medicine. “The beauty of this new technology is it can be used in many immune-related diseases. We simply change the antigen that’s delivered.”

 

“The holy grail is to develop a therapy that is specific to the pathological immune response, in this case the body attacking myelin,” Miller added. “Our approach resets the immune system so it no longer attacks myelin, but leaves the function of the normal immune system intact.“



Read original article » Back to category

Comments



 

Recent headlines

  • Posted in Software on 2017-03-25 14:13:38
    Google Develops A Deep Learning Machine That Could Learn.....read more
    Posted in Medicine on 2017-03-25 14:26:25
    Google’s Calico partners with new biotech firm to.....read more
    Posted in Business on 2017-03-25 14:20:19
    25 US Cities Are Now Committed to 100% Renewable Energy..read more
    Posted in Science on 2017-03-25 14:16:44
    New Lenses Could Give You Super Color Vision..read more
    Posted in Business on 2017-03-24 19:18:37
    This company replaced 90% of its workforce with machines......read more
Posted in Business on 2013-10-10 01:33
China is working towards a manned lunar mission in about.....read more
Posted in Business on 2013-10-20 07:17
Spacex says China is their main competitor for commercial.....read more
Posted in Software on 2013-10-20 06:43
Pirate Bay Browser Clocks 1,000,000 Downloads..read more
Posted in Medicine on 2013-10-10 02:10
Google reportedly investing hundreds of millions into new.....read more
Posted in Medicine on 2013-10-14 03:13
Endothelial Cells Can Repair and Regenerate Organs,.....read more
Posted in Science on 01.01.2010
Spacex says China is their main competitor for commercial.....read more
Posted in Science on 01.01.2010
Staring at Your Phone Could Be Making You Short Sighted..read more
Posted in Science on 01.01.2010
Oculus Rift virtual reality headset coming to mobile, but.....read more
Posted in Science on 01.01.2010
China is working towards a manned lunar mission in about.....read more
Posted in Science on 01.01.2010
Delivering drugs via nanoparticles to target mitochondria..read more

Recent Blog Posts

  • Posted by AlexMuller
    Intensive medical treatment can reverse type 2 diabetes..read more
    Posted by AlexMuller
    Daily consumption of tea protects the elderly from cognitive.....read more
    Posted by AlexMuller
    New analysis method of metabolites accurately predicts whether.....read more
    Posted by AlexMuller
    Unproven stem cell 'therapy' blinds three patients at Florida.....read more
    Posted by AlexMuller
    Indigenous South American group has healthiest arteries of all.....read more

Login to your Account

Login to your PlanetTech Account here

Username:
Password:
Remember me
or

Create a New Account

You just need username and password

The following errors occured:
Username:
Email:
Password:
Verify password:
Remember me