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Promising results for Ebola Vaccine

RATE THIS! +40
Posted in Science on 25th Dec, 2014 08:34 PM by AlexMuller

A vaccine against Ebola has shown promising results in volunteers in Uganda. The study is the first to report an Ebola vaccine candidate to be both safe and effective in an African population, said lead author Julie Ledgerwood in a statement. Ledgerwood specializes in testing experimental vaccines for the U.S. National Institute of Allergy and Infectious Disease.

 

The results are exciting because there aren't any fully proven Ebola immunizations or treatments. Hopefully, some will be ready by 2015. But there's still plenty of work left to do. Because the vaccine they tested is so new, Ledgerwood and her team gave test subjects low-potency doses of it. The dose was not enough to give the volunteers long-lasting protection against Ebola, and about half of the test subjects who received the vaccine didn't get any protection at all. However, the fact that the low-potency vaccine gave about half of people short-term protection, while triggering few side effects, is good news.
 
Normally, with results like this, the next step would be to try higher or more potent doses. In this case, public health officials have fast-tracked the development and testing of Ebola treatments, so studies of more potent versions of this vaccine are already underway. Just last month, researchers working on one of those trials published promising results from 20 study volunteers. (The trial being reported today tested 108 volunteers and included volunteers receiving a placebo. The 20-person trial included no placebo.)
 
The vaccine Ledgerwood's team is reporting on today contains a fragment of Ebola DNA. The DNA codes for the proteins that pepper the surfaces of Ebolaviruses of the Sudan and Zaire strains. Those surface proteins alone aren't enough to make people sick with Ebola, but exposing the body to them helps the immune system learn to quickly recognize those proteins and clear them out.

Tags: Eboladiseasevaccinehealthmedicine

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Comments

Author: Guest
Posted: 2014-12-26
+1
As with other infectious diseases vaccination is the key step in stoping infection spreading. Developing effective and low risk vaccines is however complex task that needs some time for a correct assessment - work will continue and hopefully succeed
2 Replies
Author: Guest
Posted: 2014-12-26
+1
Yes, this vaccine needs to be safe and efficient and well tested before the mass production - hopefully before the next epidemic round Reply
Author: Guest
Posted: 2014-12-26
+1
I believe that such goal is achievable and if successful some funding has to be available for the vaccination programme Reply
Reply
Author: Guest
Posted: 2014-12-26
+0
Great news! It looks that help is coming and that new epidemics could be prevented Reply


 

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