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Researchers create miniature human retina in a dish

RATE THIS! +37
Posted in Science on 12th Jun, 2014 12:59 AM by AlexMuller

The work, reported online June 10 “advances opportunities for vision-saving research and may ultimately lead to technologies that restore vision in people with retinal diseases,” says study leader M. Valeria Canto-Soler, Ph.D., an assistant professor of ophthalmology at the Johns Hopkins University School of Medicine.

 
The achievement emerged from experiments with human induced pluripotent stem cells (iPS). While the system doesn’t yet produce images, it could eventually enable genetically engineered retinal cell transplants that halt or even reverse a patient’s march toward blindness, the researchers say.
 
The iPS cells are adult cells that have been genetically reprogrammed to their most primitive state. Under the right circumstances, they can develop into most or all of the 200 cell types in the human body. In this case, the Johns Hopkins team turned them into retinal progenitor cells destined to form light-sensitive retinal tissue that lines the back of the eye.
 
Canto-Soler says that the newly developed system gives them the ability to generate hundreds of mini-retinas at a time directly from a person affected by a particular retinal disease such as retinitis pigmentosa. This provides a unique biological system to study the cause of retinal diseases directly in human tissue, instead of relying on animal models.
 
The system, she says, also opens an array of possibilities for personalized medicine such as testing drugs to treat these diseases in a patient-specific way. In the long term, the potential is also there to replace diseased or dead retinal tissue with lab-grown material to restore vision.

Tags: eyeretinastem cellsregenerative medicine

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Comments

Author: Guest
Posted: 2014-06-12
+3
Regenerative medicine and stem cells are starting to make good progress! This work on retina is very promising and and hopefully will change lives of many people with affected eye site in the near future
1 Replies
Author: Guest
Posted: 2014-06-12
+1
At the first instance, this opens an array of possibilities for personalized medicine such as testing drugs to treat these diseases in a patient-specific way. In the long term, the potential is also there to replace diseased or dead retinal tissue with lab-grown material to restore vision. Reply
Reply
Author: Guest
Posted: 2014-06-23
+0
a little bit more about the "shortness of brteah" symptom. In other words - I tried to read it as a regular reader would (being formerly a nurse and having to do patient instruction I try to look for things that patients might misinterpret) and I was thinking... what do they mean by "shortness of brteah"? In other words - how much or about how much exertion should a normal person be able to handle? Are we talking a walk across the room? A walk out to the mailbox? That kind of thing. It's very confusing to people when these things aren't explained properly. They may be concerned if they read this and they're out of shape thus out of brteah by climbing stairs... which would be normal for someone who doesn't exercise... and while it indicates they need to do some exercise, that might not indicate actual heart problems. Those who have experienced heart problems might think it's obvious... it really isn't to those who have never dealt with it at all... and WebMD is meant to give information to people who are not medical people. As for BP - mine runs very low too generally the low hundreds over 60. A couple of years ago I had to go to a treatment center for a really bad migraine (I was in the middle of traveling and couldn't continue without medication) and my BP during an all out session of extreme pain was 90/50 I figured it would certainly be like 140/80 or something outrageous. First time I ever had a BP during a heavy duty headache. Reply
Author: Guest
Posted: 2015-02-18
+0
Nike Air Max : Faites vos choix de Nike Air Max parmi les produits de nombreuses marques et boutiques en ligne ► ► Nike Air Max Reply
Author: Guest
Posted: 2015-02-18
+0
reconnaitre un vrai sac chlo paraty De sacs à main designer, tels que les sacs à bandoulière, fourre-tout, embrayages, les vagabonds, crossbodies, les sacs de soirée pour sacs à main en cuir de luxe, se laisser emporter par notre choix incomparable de concepteur sacs à main de louis vuitton, lancel, gucci, Céline, hermes, prada, kors michael, chanel, burberry, longchmap, guess, chloe, longchamp, céline, dolce&gabbana, miu miu, furla et plus encore! Assurez-vous que vous ne manquez pas. Reply
Author: Guest
Posted: 2015-02-18
+0
Les sacs Longchamp sont, depuis toujours, réputés pour être à la fois pratiques et ultra-tendance ! Citons pour commencer le cultissime modèle "Pliage" inspiré Reply
Author: Guest
Posted: 2016-05-06
+0
wey pencaci shadapp! pi mampos dia la nak ubah muka dia ke, body dia ke. yang korean gurl semua ubah muka korang puji tahap langit ke7 boleh pulak.. keantiah. Reply
Author: Guest
Posted: 2016-05-06
+0
wey pencaci shadapp! pi mampos dia la nak ubah muka dia ke, body dia ke. yang korean gurl semua ubah muka korang puji tahap langit ke7 boleh pulak.. keantiah. Reply


 

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