Social Media Sidebar


Please sign up, comment on articles and bring your friends!

Current poll

PlanetTech is asking:

What do you think about our new web site?

Love it, indeed
Really good solution
Same as old one
The old one was better
This is a new option

Quote of the day

When seen through the lens of technology, few resources are truly scarce; they’re mainly inaccessible. 


Peter Diamandis

Researchers regrow human corneas in mice

Posted in Science on 8th Jul, 2014 01:44 AM by AlexMuller

Researchers has identified a way to trigger regrowth of human corneal tissue using stem cells. The finding could restore vision for victims of injury and others with damaging eye diseases. Limbal stem cells, which reside in the eye’s limbus, help maintain and regenerate corneal tissue. Their loss due to injury or disease is one of the leading causes of blindness.

In the past, tissue or cell transplants have been used to help the cornea regenerate, but it was unknown whether there were actual limbal stem cells in the grafts, or how many, and the outcomes were not consistent.
In this new study, researchers at the Massachusetts Eye and Ear/Schepens Eye Research Institute (Mass. Eye and Ear), Boston Children’s Hospital, Brigham and Women’s Hospital, and the VA Boston Healthcare System used a molecule known as ABCB5, which acts as a marker for hard-to-find limbal stem cells.
ABCB5 allowed the researchers to locate hard-to-find limbal stem cells in tissue from deceased human donors and use these stem cells to regrow anatomically correct, fully functional human corneas in mice.
“Limbal stem cells are very rare, and successful transplants are dependent on these rare cells,” says Bruce Ksander, Ph.D., of Mass. Eye and Ear, co-lead author on the study with post-doctoral fellow Paraskevi Kolovou, M.D. “This finding will now make it much easier to restore the corneal surface. It’s a very good example of basic research moving quickly to a translational application.”

Tags: eyecorneablindnessstem cellsvision

Read original article » Back to category


Author: Guest
Posted: 2014-07-08
Regenerative medicine is making great progress and steam cells are the key. Finding accurate markers is one important step and it seems that identifying ABCB5 is this study made further application possible. Well done!
2 Replies
Author: Guest
Posted: 2014-07-08
Until now, no molecular marker existed for limbal stem cells by which these rare cells could be isolated and purified. Previously published work on limbal epithelial cell grafts showed that when more than three percent of transplanted cells were stem cells, transplants were successful — less than three percent and the transplants were not. The ABCB5 marker for limbal stem cells will help that future procedures are efficient. Reply


Recent headlines

  • Posted in Software on 2018-03-16 11:03:28
    60.3% of harmful Android apps in 2017 detected more
    Posted in Hardware on 2018-03-16 11:00:28
    Big harpoon is 'solution to space junk' more
    Posted in Science on 2018-03-16 10:58:40
    Russia will beat NASA to mars and find water on the moon, more
    Posted in Business on 2018-03-14 07:02:30
    X Prize announces $10 million competition to more
    Posted in Business on 2018-03-14 06:57:20
    How to spot a cryptocurrency more
Posted in Business on 2013-10-10 01:33
China is working towards a manned lunar mission in more
Posted in Business on 2013-10-20 07:17
Spacex says China is their main competitor for more
Posted in Software on 2013-10-20 06:43
Pirate Bay Browser Clocks 1,000,000 more
Posted in Medicine on 2013-10-10 02:10
Google reportedly investing hundreds of millions into more
Posted in Medicine on 2013-10-14 03:13
Endothelial Cells Can Repair and Regenerate Organs, more
Posted in Science on 01.01.2010
Spacex says China is their main competitor for more
Posted in Science on 01.01.2010
Staring at Your Phone Could Be Making You Short more
Posted in Science on 01.01.2010
Oculus Rift virtual reality headset coming to mobile, more
Posted in Science on 01.01.2010
China is working towards a manned lunar mission in more
Posted in Science on 01.01.2010
Delivering drugs via nanoparticles to target more

Recent Blog Posts

  • Posted by AlexMuller
    Martian landscapes formed from sand 'levitating' on a more
    Posted by AlexMuller
    Scientists detect comets outside our solar more
    Posted by AlexMuller
    Advanced artificial limbs mapped in the more
    Posted by AlexMuller
    Bacteria have a sense of more
    Posted by AlexMuller
    Recurrent brain cancer: New hope with phase 1 clinical more

Login to your Account

Login to your PlanetTech Account here

Remember me

Create a New Account

You just need username and password

The following errors occured:
Verify password:
Remember me