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Quote of the day

'By far the greatest danger of Artificial Intelligence is that people conclude too early that they understand it'

 

Eliezer Yudkowsky

Science enters $1,000 genome era

RATE THIS! +46
Posted in Science on 15th Jan, 2014 09:30 PM by AlexMuller

The ability to sequence a human genome for just $1,000 has arrived, a US genetic technology company has announced. San Diego-based Illumina says it is to release a new sequencing machine that can deliver five whole genomes in a day. The race to unlock a human's genetic blueprint for $1,000 has been underway for more than a decade. 

 

The Archon X-prize had offered $10m for a team that reached or came closest, until it was cancelled in August 2013.

 
The term was thought up as a symbolic landmark that would, in theory, light the fires of a long-anticipated revolution in personalised medicine.
 
The HiSeq X Ten high throughput genetic sequencing machine was announced at the annual JP Morgan Healthcare Conference in San Francisco this week. The company said it had broken the "sound barrier" of human genomics.
 
In his presentation at the meeting, Illumina's chief executive Jay Flatley said the HiSeq X Ten would improve on the scanning speed of its predecessor by a factor of six. This would offer the ability to sequence five whole human genomes in a single day, Bio-IT World reported.
 
He said the $1m sequencers (sold in a minimum of 10 units) would be able to deliver a genome for just under $1,000, consistent with calculations the National Human Genome Research Institute uses to estimate sequencing costs.

Tags: genegeneticsgenomicsgenomehealthbioinformaticsX-prize

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Comments

Author: Guest
Posted: 2014-01-16
+2
This is great step towards understanding genetic causes of a number of diseases and for prospects of personalised medicine
3 Replies
Author: Guest
Posted: 2014-01-16
+0
I agree. The HiSeq X Ten platform should give us the ability to analyse complete genomic information from huge sample populations. Reply
Author: Guest
Posted: 2014-01-16
+0
I believe that new and cheaper methods to sequence DNA of entire genomes are providing very important resource in many fields of biology - from evolution to ageing. However it is not easy to convert these data into information but this is also coming Reply
Reply
Author: Guest
Posted: 2014-01-16
+0
In the last few years, the decline in the cost of genome sequencing had outpaced the famous Moore's Law for computer processors. Nevertheless, the target " $1,000 genome" proved difficult to reach. Reply
Author: Guest
Posted: 2014-01-16
+0
As they pointed out, the world was "entering the supersonic age of genomics".
1 Replies
Author: Guest
Posted: 2014-01-16
+0
Yes, the first human genome wasn’t sequenced until 2003, after 16 years and nearly $3 billion. Reply
Reply
Author: Guest
Posted: 2014-01-16
+1
This approach is the key to understand genetic underpinnings of diseases and requires powerful computers. Many genome-wide studies conducted so far helped to associate specific genes with numerous diseases that have been investigated in this way.
1 Replies
Author: Guest
Posted: 2014-01-16
+0
Yes, there is a big effort, for example in cancer. The Cancer Genome Atlas is assembling thousands of genomes to discover the genetic causes of cancer. Reply
Reply
Author: Guest
Posted: 2014-01-16
+0
Yes, medical research has largely focused on finding genetic markers of disease. The genetics of good health are also important. We should try to understand the mechanisms that help keep people healthy and protected from disease, and to translate key discoveries into improvements in patient care.
3 Replies
Author: Guest
Posted: 2014-01-16
+0
Looking at the genes of healthy elderly people is a unique approach to understanding the underpinning biology of health, and ways this can be inherited. Also very important Reply
Author: Guest
Posted: 2014-01-16
+0
Yes, they believe that the older an individual gets without developing an age-related disease, the more likely the contributing factors are genetic and this type of study is very relevant Reply
Reply


 

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