Social Media Sidebar

Announcement

Please sign up, comment on articles and bring your friends!

Current poll

PlanetTech is asking:

What do you think about our new web site?

Love it, indeed
Really good solution
Same as old one
The old one was better
This is a new option

Quote of the day

'By far the greatest danger of Artificial Intelligence is that people conclude too early that they understand it'

 

Eliezer Yudkowsky

Scientists grow miniature human stomachs from stem cells

RATE THIS! +44
Posted in Science on 30th Oct, 2014 10:50 PM by AlexMuller

Scientists have grown miniature human stomachs from stem cells as a way of studying gastric diseases such as ulcers and stomach cancer and in the future creating tissue to repair patients’ stomachs. The mini-stomachs are grown in petri dishes from stem cells. Fully formed, they are the size of a pea and shaped like a rugby ball.

 

They are hollow with an interior lining that is folded into glands and pits like a real stomach. Crucially, the researchers found that the miniature stomachs, known as gastric organoids, respond to infection very much like ordinary human stomachs. “There hasn’t been any good way to study human stomach disease before because animals just don’t get the same diseases,” said James Wells, director of the Pluripotent Stem Cell Facility, Cincinnati Children’s Hospital Medical Center, who led the research which is published in Nature.

 
Human gastric diseases are associated with chronic infection by the bacterium Helicobacter pylori. Half the world’s population is infected with the bug, which can be picked up from food. Although most people do not show symptoms, once the infection is present up to 20% of carriers will develop gastric ulcers during their lifetimes. Around 2% will develop stomach cancer.
 
In developing countries, where H. pylori infection is more prevalent, gastric cancers are the second leading cause of cancer-related deaths. Having grown the mini-stomachs, the researchers then injected them with H. pylori. In animals, H. pylori has little effect and disease does not follow but in the gastric organoid, the invading bacteria behaved as if it were a real human stomach.

Tags: medicinestem cellsregenerative medicinestomach

Read original article » Back to category

Comments

Author: Guest
Posted: 2014-10-31
+2
Great progress. Assembling tissues that fatefully reproduced function of human organs like these gastric organoids is a big step forward. They will replace animal testing that is its desirable and importantly will achieve accuracy with respect to human condition
1 Replies
Author: Guest
Posted: 2014-10-31
+1
Yes, infection of human cells with H. pylori was not possible before - this will be the way to tackle the disease Reply
Reply
Author: Guest
Posted: 2014-10-31
+1
Indeed, significant progress. Furthermore, this is not the first time that miniature organs have been grown from stem cells. In 2013, scientists grew miniature kidneys and successfully transplanted into a rat. Replacement windpipes, grown from stem cells on lab-made scaffolds, have also been grown and transplanted into patients. Reply
Author: Guest
Posted: 2014-10-31
+0
There many other exciting applications. The stomach researchers are now investigating whether their technique can be used to grow replacement stomach tissues for repairing ulcers, which are effectively holes in the stomach’s lining. Reply


 

Recent headlines

  • Posted in Business on 2017-03-26 19:56:28
    The U.S. will be hit worse by job automation than other.....read more
    Posted in Business on 2017-03-26 19:49:51
    Elon Musk says Tesla will start taking orders for Solar.....read more
    Posted in Science on 2017-03-26 19:39:27
    Impact crater linked to Martian tsunamis..read more
    Posted in Software on 2017-03-25 14:13:38
    Google Develops A Deep Learning Machine That Could Learn.....read more
    Posted in Medicine on 2017-03-25 14:26:25
    Google’s Calico partners with new biotech firm to.....read more
Posted in Business on 2013-10-10 01:33
China is working towards a manned lunar mission in about.....read more
Posted in Business on 2013-10-20 07:17
Spacex says China is their main competitor for commercial.....read more
Posted in Software on 2013-10-20 06:43
Pirate Bay Browser Clocks 1,000,000 Downloads..read more
Posted in Medicine on 2013-10-10 02:10
Google reportedly investing hundreds of millions into new.....read more
Posted in Medicine on 2013-10-14 03:13
Endothelial Cells Can Repair and Regenerate Organs,.....read more
Posted in Science on 01.01.2010
Spacex says China is their main competitor for commercial.....read more
Posted in Science on 01.01.2010
Staring at Your Phone Could Be Making You Short Sighted..read more
Posted in Science on 01.01.2010
Oculus Rift virtual reality headset coming to mobile, but.....read more
Posted in Science on 01.01.2010
China is working towards a manned lunar mission in about.....read more
Posted in Science on 01.01.2010
Delivering drugs via nanoparticles to target mitochondria..read more

Recent Blog Posts

  • Posted by AlexMuller
    Intensive medical treatment can reverse type 2 diabetes..read more
    Posted by AlexMuller
    Daily consumption of tea protects the elderly from cognitive.....read more
    Posted by AlexMuller
    New analysis method of metabolites accurately predicts whether.....read more
    Posted by AlexMuller
    Unproven stem cell 'therapy' blinds three patients at Florida.....read more
    Posted by AlexMuller
    Indigenous South American group has healthiest arteries of all.....read more

Login to your Account

Login to your PlanetTech Account here

Username:
Password:
Remember me
or

Create a New Account

You just need username and password

The following errors occured:
Username:
Email:
Password:
Verify password:
Remember me