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Scientists 'print' new eye cells

RATE THIS! +42
Posted in Science on 19th Dec, 2013 01:09 AM by AlexMuller

Scientists say they have been able to successfully print new eye cells that could be used to treat sight loss. The proof-of-principle work in the journal Biofabrication was carried out using animal cells. The Cambridge University team says it paves the way for grow-your-own therapies for people with damage to the light-sensitive layer of tissue at back of the eye - the retina.

 
More tests are needed before human trials can begin. At the moment the results are preliminary and show that an inkjet printer can be used to print two types of cells from the retina of adult rats―ganglion cells and glial cells.
 
These are the cells that transmit information from the eye to certain parts of the brain, and provide support and protection for neurons. The printed cells remained healthy and retained their ability to survive and grow in culture.
 
Co-authors of the study Prof Keith Martin and Dr Barbara Lorber, from the John van Geest Centre for Brain Repair at the University of Cambridge, said: "The loss of nerve cells in the retina is a feature of many blinding eye diseases. The retina is an exquisitely organised structure where the precise arrangement of cells in relation to one another is critical for effective visual function.

Tags: eyestem cellsorgan printingregenerative medicinehealthretina

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Comments

Author: Guest
Posted: 2013-12-19
+3
Eye sight is so important to people and the new method described here could be very helpful. But, as they say, early days...
6 Replies
Author: Guest
Posted: 2013-12-19
+1
This is a step in the right direction as the retina is often affected in many of the common eye conditions, causing loss of vision which stops people being part of normal life
3 Replies
Author: Guest
Posted: 2013-12-19
+2
This study demonstrates that cells derived from the mature central nervous system, the eye, can be printed using a piezoelectric inkjet printer. Although results are preliminary and much more work is still required, the aim and hope is to develop this technology for use in retinal repair in the future- very significant progress and promising application!
1 Replies
Author: Guest
Posted: 2013-12-19
+0
I agree. The finding that eye cells can survive the printing process suggests the exciting possibility that this technique could be used in the future to create organised tissues for regeneration of the eye and restoration of sight Reply
Reply
Author: Guest
Posted: 2013-12-19
+0
It would be important to find out would it be possible to print other types of retinal cells, including the light-sensitive photoreceptors - rods and cones. This would go a significant step forward to reconstruct the eye Reply
Reply
Author: Guest
Posted: 2013-12-19
+0
Application of stem cells research and further development of 3D printing good options to address these issues Reply
Author: Guest
Posted: 2013-12-19
+0
Yes, but printing biomaterial is an entirely different ball game - this is a big deal Reply
Author: Guest
Posted: 2013-12-19
+0
Bio ink is the first step to develop the protocols required to generate the multi-cellular building blocks from the cells that will be used to build the target tissue. They were successful here with cells from the retina -ganglion cells and glial cells. Reply
Author: Guest
Posted: 2013-12-19
+0
It seem that is possible to implanted a 3D-printed tooth-shaped scaffold into the jawbone of a rat and result was that the animal started naturally growing a tooth using stem cells from the body within weeks Reply
Reply
Author: Guest
Posted: 2013-12-19
+2
Bioprinting should be supported- bioprinting efforts are ongoing, funding is coming and there are already companies established based on this idea.
3 Replies
Author: Guest
Posted: 2013-12-19
+1
Organovo is very prominent in this area. Organovo’s bioprinting process centers around the identification of key elements of a target tissue, and the creation of a design that can be utilized by a bioprinter Reply
Reply
Author: Guest
Posted: 2013-12-19
+1
Scientists have already been able to reverse blindness in mice using stem cell transplants. This was reported recently
2 Replies
Author: Guest
Posted: 2013-12-19
+0
Yes, it was possible to achieve that totally blind mice had their sight restored by injections of light-sensing cells into the eye. A team in Oxford said their studies closely resemble the treatments that would be needed in people with degenerative eye disease.
Reply
Reply
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Author: Guest
Posted: 2016-05-07
+0
What a great rerosuce this text is. Reply


 

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