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Unusually Short Lived Fish Could Hold the Secrets to Getting Old

RATE THIS! +38
Posted in Science on 6th Mar, 2015 06:03 PM by AlexMuller

The turquoise killifish is largely unremarkable except for how fast it ages. In just three months, it goes from young to old one. For scientists who study ageing, the turquoise killifish could be the key to their future experiments. The fish is one of the shortest lived vertebrates in the world.

 

After a few months, writes Carl Zimmer in the New York Times, they lose muscle, become infertile, and get sick more often, not unlike humans. The vast majority of scientific research is done in a few model organisms: mice, rats, fruit flies, and a little nematode worm called Caenorhabditis elegans. Fruit flies and C. elegans are invertebrates, making many questions about ageing in humans, such as why our bones get frail as we get older, impossible to study. Mice and rats are closer to humans, but they live for years rather than months.

 
Enter the turquoise killifish, where rapid ageing is a plus rather than a minus. A Stanford lab has spent years developing it into a model organism. In a paper published recently in Cell, they detail a genetic toolkit that includes the fish's entire sequenced genome as well as the locations of several ageing-related genes. New genetic tools like CRISPR are helping scientist identify relevant genes more easily than ever. Anti-ageing drugs could also be tested on the fish.

Tags: agingbiologyfishanimalregenerative medicine

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Comments

Author: Guest
Posted: 2015-03-07
+1
This new fish model is of course helpful and is likely to make an important contribution to genetics of ageing. However, when it comes to humans it is not clear to what extent the findings from fish would be relevant Reply
Author: Guest
Posted: 2016-12-26
+0
Well the thing is that I use a mix and correlate the lot, but if you don’t have staff to do that and the budget for numerous SEO tools, I’d say using Bing WMT, Google WMT and on of the mainstream tools, Majestic, Linseekrarch Tools or Ahrefs should probably do you. Personally my favourite is actually LRT out of the paid stuff, even though the data is often a bit old and some of the links will have dropped off that in itself is useful for re-inclusion requests, tell Google you took them down XD Reply


 

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