Social Media Sidebar

Announcement

Please sign up, comment on articles and bring your friends!

Current poll

PlanetTech is asking:

What do you think about our new web site?

Love it, indeed
Really good solution
Same as old one
The old one was better
This is a new option

Quote of the day

When seen through the lens of technology, few resources are truly scarce; they’re mainly inaccessible. 

 

Peter Diamandis

Tiny wireless LED activates neurons to release dopamine

RATE THIS! +11
Posted in Science on 16th Apr, 2013 12:36 AM by AlexMuller

“This strategy should allow us to identify and map brain circuits involved in complex behaviors related to sleep, depression, addiction, and anxiety,” says co-principal investigator Michael R. Bruchas, PhD, assistant professor of anesthesiology at Washington University.

 

“Understanding which populations of neurons are involved in these complex behaviors may allow us to target specific brain cells that malfunction in depression, pain, addiction and other disorders.”

 

For the study, Washington University neuroscientists teamed with engineers at the University of Illinois to design multicolored microscale, inorganic light-emitting diodes (µILEDs) that are just 6.45 microns (micrometers, or millionths of a meter) thick (thinner than a human hair) and and 50 × 50 µm square. The µILEDs are less than one-thousandth the size of conventional LEDs (typically 100 mm thick with lateral dimensions of 1 mm square).

 

The small sizes of µILEDs allow for spatially precise cellular-scale delivery of photons, highly effective
thermal management, reduced tissue damage, and minimized inflammation for prolonged use
in vivo.

 

This was the first application of the devices in optogenetics, which uses light to stimulate targeted pathways in the brain. The scientists implanted them into the brains of mice that had been genetically engineered so that some of their brain cells could be activated and controlled with light.

 

Although a number of important pathways in the brain can be studied with optogenetics, many neuroscientists have struggled with the engineering challenge of delivering light to precise locations deep in the brain. Most methods have tethered animals to lasers with fiber optic cables, limiting their movement and altering natural behaviors.

 

But with the new devices, the mice freely moved about and were able to explore a maze or scamper on a wheel. The electronic µLEDs are housed in a tiny fiber implanted deep in the brain. Moving freely is important to the device’s ability to activate the proper neurons, according to John A. Rogers, PhD, professor of materials science and engineering at the University of Illinois.



Read original article » Back to category

Comments



 

Recent headlines

  • Posted in Medicine on 2017-11-21 09:01:15
    High Incidence of PTSD Among Cancer Patients..read more
    Posted in Science on 2017-11-21 08:56:02
    Human Memory Enhanced With a Brain Implant For the First.....read more
    Posted in Hardware on 2017-11-21 08:51:13
    MIT Reveals a Battery That Stores Solar Energy to Make.....read more
    Posted in Science on 2017-11-21 08:45:29
    Japan discovers new 50km cave in moon, raises hope for.....read more
    Posted in Software on 2017-11-20 17:24:02
    The 3 biggest threats to your Bitcoin (and 10 tips to.....read more
Posted in Business on 2013-10-10 01:33
China is working towards a manned lunar mission in about.....read more
Posted in Business on 2013-10-20 07:17
Spacex says China is their main competitor for commercial.....read more
Posted in Software on 2013-10-20 06:43
Pirate Bay Browser Clocks 1,000,000 Downloads..read more
Posted in Medicine on 2013-10-10 02:10
Google reportedly investing hundreds of millions into new.....read more
Posted in Medicine on 2013-10-14 03:13
Endothelial Cells Can Repair and Regenerate Organs,.....read more
Posted in Science on 01.01.2010
Spacex says China is their main competitor for commercial.....read more
Posted in Science on 01.01.2010
Staring at Your Phone Could Be Making You Short Sighted..read more
Posted in Science on 01.01.2010
Oculus Rift virtual reality headset coming to mobile, but.....read more
Posted in Science on 01.01.2010
China is working towards a manned lunar mission in about.....read more
Posted in Science on 01.01.2010
Delivering drugs via nanoparticles to target mitochondria..read more

Recent Blog Posts

  • Posted by AlexMuller
    Martian landscapes formed from sand 'levitating' on a little.....read more
    Posted by AlexMuller
    Scientists detect comets outside our solar system..read more
    Posted by AlexMuller
    Advanced artificial limbs mapped in the brain..read more
    Posted by AlexMuller
    Bacteria have a sense of touch..read more
    Posted by AlexMuller
    Recurrent brain cancer: New hope with phase 1 clinical trial.....read more

Login to your Account

Login to your PlanetTech Account here

Username:
Password:
Remember me
or

Create a New Account

You just need username and password

The following errors occured:
Username:
Email:
Password:
Verify password:
Remember me